Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 494767..495467 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag PKO50_RS02340 Protein ID WP_275628696.1
Coordinates 494767..495063 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag PKO50_RS02345 Protein ID WP_089389665.1
Coordinates 495066..495467 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS02310 491019..491906 - 888 WP_109933205.1 methylisocitrate lyase -
PKO50_RS02315 491903..492625 - 723 WP_089389670.1 GntR family transcriptional regulator -
PKO50_RS02320 492822..493433 + 612 WP_275628694.1 class I SAM-dependent methyltransferase -
PKO50_RS02325 493441..493680 - 240 WP_009615991.1 hypothetical protein -
PKO50_RS02330 493846..494076 - 231 WP_009615992.1 hypothetical protein -
PKO50_RS02335 494188..494640 - 453 WP_275628695.1 hypothetical protein -
PKO50_RS02340 494767..495063 + 297 WP_275628696.1 type II toxin-antitoxin system MqsR family toxin Toxin
PKO50_RS02345 495066..495467 + 402 WP_089389665.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PKO50_RS02350 495919..497247 - 1329 WP_109934197.1 sigma-54 dependent transcriptional regulator -
PKO50_RS02355 497244..499130 - 1887 WP_275628697.1 sensor histidine kinase -
PKO50_RS02360 499333..500067 - 735 WP_089389662.1 amino acid ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10926.68 Da        Isoelectric Point: 8.9848

>T269235 WP_275628696.1 NZ_CP116775:494767-495063 [Pseudomonas sp. 273]
MEKSTPHCRLDRVKSLLAQGRVRATYSALSGGAVLGLDFADMLAVIEALAPRDFHKSMTTHADHRVWQDVYRPSTAVGRI
YLKLTVIDDVLVVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14447.68 Da        Isoelectric Point: 7.0843

>AT269235 WP_089389665.1 NZ_CP116775:495066-495467 [Pseudomonas sp. 273]
MKCPLCGGAELLHETRDLPYAYKGESTLITAVRGEFCPACGEAVLDADESARVSAQMLAFNKRVNASMVDPGFIAAVRKK
LALDQREAAEIFGGGVNAFSRYENGKTRPPLALVKLLKVLDRHPELLEEVRSG

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References