Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1812909..1813429 Replicon chromosome
Accession NZ_CP116735
Organism Agrobacterium pusense strain CFBP5496

Toxin (Protein)


Gene name yoeB Uniprot ID A0A098RUX8
Locus tag CFBP5496_RS09450 Protein ID WP_037089950.1
Coordinates 1812909..1813178 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A098RWL5
Locus tag CFBP5496_RS09455 Protein ID WP_037089948.1
Coordinates 1813175..1813429 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5496_RS09430 (CFBP5496_0009430) 1807915..1809609 - 1695 WP_037089954.1 iron ABC transporter permease -
CFBP5496_RS09435 (CFBP5496_0009435) 1809619..1810602 - 984 WP_037089952.1 ABC transporter substrate-binding protein -
CFBP5496_RS09440 (CFBP5496_0009440) 1810938..1812182 - 1245 WP_004442697.1 PLP-dependent aminotransferase family protein -
CFBP5496_RS09445 (CFBP5496_0009445) 1812455..1812904 + 450 WP_037089951.1 RbsD/FucU family protein -
CFBP5496_RS09450 (CFBP5496_0009450) 1812909..1813178 - 270 WP_037089950.1 Txe/YoeB family addiction module toxin Toxin
CFBP5496_RS09455 (CFBP5496_0009455) 1813175..1813429 - 255 WP_037089948.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CFBP5496_RS09460 (CFBP5496_0009460) 1813567..1814586 - 1020 WP_003495030.1 ketol-acid reductoisomerase -
CFBP5496_RS09465 (CFBP5496_0009465) 1814636..1815289 - 654 WP_004442706.1 TetR/AcrR family transcriptional regulator -
CFBP5496_RS09470 (CFBP5496_0009470) 1815686..1816591 - 906 WP_037089946.1 AraC family transcriptional regulator -
CFBP5496_RS09475 (CFBP5496_0009475) 1816781..1817827 + 1047 WP_125269969.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10612.09 Da        Isoelectric Point: 9.8742

>T269222 WP_037089950.1 NZ_CP116735:c1813178-1812909 [Agrobacterium pusense]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRISAEHRFVYRVSGSGSEQRLE
IIQCRFHYQ

Download         Length: 270 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9702.92 Da        Isoelectric Point: 4.6631

>AT269222 WP_037089948.1 NZ_CP116735:c1813429-1813175 [Agrobacterium pusense]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANALRLRTSMDQLERGDIIERD
PTEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A098RUX8

Antitoxin

Source ID Structure
AlphaFold DB A0A098RWL5

References