Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1758084..1758604 Replicon chromosome
Accession NZ_CP116692
Organism Agrobacterium tumefaciens strain A74a

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag G6M15_RS08885 Protein ID WP_174008824.1
Coordinates 1758084..1758353 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag G6M15_RS08890 Protein ID WP_174008825.1
Coordinates 1758350..1758604 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6M15_RS08865 (G6M15_08865) 1753113..1754807 - 1695 WP_174008820.1 iron ABC transporter permease -
G6M15_RS08870 (G6M15_08870) 1754817..1755800 - 984 WP_174008821.1 ABC transporter substrate-binding protein -
G6M15_RS08875 (G6M15_08875) 1756111..1757355 - 1245 WP_174008822.1 PLP-dependent aminotransferase family protein -
G6M15_RS08880 (G6M15_08880) 1757630..1758079 + 450 WP_174008823.1 RbsD/FucU family protein -
G6M15_RS08885 (G6M15_08885) 1758084..1758353 - 270 WP_174008824.1 Txe/YoeB family addiction module toxin Toxin
G6M15_RS08890 (G6M15_08890) 1758350..1758604 - 255 WP_174008825.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G6M15_RS08895 (G6M15_08895) 1758743..1759762 - 1020 WP_174008826.1 ketol-acid reductoisomerase -
G6M15_RS08900 (G6M15_08900) 1759807..1760460 - 654 WP_003513063.1 TetR/AcrR family transcriptional regulator -
G6M15_RS08905 (G6M15_08905) 1760857..1761762 - 906 WP_174008827.1 AraC family transcriptional regulator -
G6M15_RS08910 (G6M15_08910) 1761952..1762998 + 1047 WP_174008828.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-88)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10626.12 Da        Isoelectric Point: 9.8742

>T269131 WP_174008824.1 NZ_CP116692:c1758353-1758084 [Agrobacterium tumefaciens]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRITAEHRFVYRVSGSGSEQRLE
IIQCRFHYQ

Download         Length: 270 bp


Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9605.76 Da        Isoelectric Point: 4.6749

>AT269131 WP_174008825.1 NZ_CP116692:c1758604-1758350 [Agrobacterium tumefaciens]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANASRLRVSMGELERGDTIERD
PTEE

Download         Length: 255 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References