Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2055431..2056018 Replicon chromosome
Accession NZ_CP116683
Organism Agrobacterium fabrum strain 2788

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag G6L39_RS10185 Protein ID WP_080807502.1
Coordinates 2055431..2055715 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag G6L39_RS10190 Protein ID WP_080807499.1
Coordinates 2055767..2056018 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L39_RS10160 (G6L39_010160) 2050910..2051524 - 615 WP_244520223.1 hypothetical protein -
G6L39_RS10165 (G6L39_010165) 2051711..2052844 + 1134 WP_167305544.1 alpha-hydroxy acid oxidase -
G6L39_RS10170 (G6L39_010170) 2053041..2053385 - 345 WP_006311727.1 multidrug efflux SMR transporter -
G6L39_RS10175 (G6L39_010175) 2053382..2053966 - 585 WP_010972227.1 TetR/AcrR family transcriptional regulator -
G6L39_RS10180 (G6L39_010180) 2054156..2055427 + 1272 WP_167305628.1 D-alanyl-D-alanine carboxypeptidase -
G6L39_RS10185 (G6L39_010185) 2055431..2055715 - 285 WP_080807502.1 Txe/YoeB family addiction module toxin Toxin
G6L39_RS10190 (G6L39_010190) 2055767..2056018 - 252 WP_080807499.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G6L39_RS10195 (G6L39_010195) 2056071..2056820 - 750 WP_080807496.1 metallophosphoesterase family protein -
G6L39_RS10200 (G6L39_010200) 2056826..2057182 - 357 WP_006311723.1 hydroxyisourate hydrolase -
G6L39_RS10205 (G6L39_010205) 2057179..2057679 - 501 WP_173992757.1 ureidoglycolate lyase -
G6L39_RS10210 (G6L39_010210) 2057683..2058045 - 363 WP_010972232.1 DUF86 domain-containing protein -
G6L39_RS10215 (G6L39_010215) 2058042..2058335 - 294 WP_010972233.1 nucleotidyltransferase family protein -
G6L39_RS10220 (G6L39_010220) 2058389..2058886 - 498 WP_080807490.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
G6L39_RS10225 (G6L39_010225) 2058886..2059809 - 924 WP_080807485.1 allantoinase PuuE -
G6L39_RS10230 (G6L39_010230) 2060011..2060718 - 708 WP_080807479.1 DUF1045 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11487.22 Da        Isoelectric Point: 9.5189

>T269122 WP_080807502.1 NZ_CP116683:c2055715-2055431 [Agrobacterium fabrum]
MQQKGTIALGWSHEGWEDYLHWQKYDRKMLERINELIKDCRRHPFEGIGKPEPLRFQLKGLWSRRISQEHRLVYELRGDG
EKAVLIIHQCRFHY

Download         Length: 285 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9394.61 Da        Isoelectric Point: 4.5242

>AT269122 WP_080807499.1 NZ_CP116683:c2056018-2055767 [Agrobacterium fabrum]
MRTVIFSKARESLASLLDEVSQDRVAVEIVRRDKPSAVLIDKDEYEGLLETLHLCSSPENFARLRKSMSDVDTGVFESHD
LID

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References