Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1738192..1738712 Replicon chromosome
Accession NZ_CP116683
Organism Agrobacterium fabrum strain 2788

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag G6L39_RS08690 Protein ID WP_080808022.1
Coordinates 1738192..1738461 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag G6L39_RS08695 Protein ID WP_080808019.1
Coordinates 1738458..1738712 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L39_RS08670 (G6L39_008670) 1733227..1734921 - 1695 WP_092731507.1 iron ABC transporter permease -
G6L39_RS08675 (G6L39_008675) 1734931..1735914 - 984 WP_080808034.1 ABC transporter substrate-binding protein -
G6L39_RS08680 (G6L39_008680) 1736220..1737464 - 1245 WP_080808028.1 PLP-dependent aminotransferase family protein -
G6L39_RS08685 (G6L39_008685) 1737738..1738187 + 450 WP_080808025.1 RbsD/FucU family protein -
G6L39_RS08690 (G6L39_008690) 1738192..1738461 - 270 WP_080808022.1 Txe/YoeB family addiction module toxin Toxin
G6L39_RS08695 (G6L39_008695) 1738458..1738712 - 255 WP_080808019.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G6L39_RS08700 (G6L39_008700) 1738851..1739870 - 1020 WP_010972004.1 ketol-acid reductoisomerase -
G6L39_RS08705 (G6L39_008705) 1739918..1740571 - 654 WP_080808016.1 TetR/AcrR family transcriptional regulator -
G6L39_RS08710 (G6L39_008710) 1740944..1741849 - 906 WP_006311840.1 AraC family transcriptional regulator -
G6L39_RS08715 (G6L39_008715) 1742039..1743085 + 1047 WP_080808012.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10611.15 Da        Isoelectric Point: 9.8742

>T269120 WP_080808022.1 NZ_CP116683:c1738461-1738192 [Agrobacterium fabrum]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRITAEHRFVYRVSGSGSEQRLE
IIQCRFHYL

Download         Length: 270 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9692.84 Da        Isoelectric Point: 4.6882

>AT269120 WP_080808019.1 NZ_CP116683:c1738712-1738458 [Agrobacterium fabrum]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANASRLRASMDELERDDTIERD
PTEK

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References