Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5140103..5140692 Replicon chromosome
Accession NZ_CP116672
Organism Xanthomonas hortorum pv. pelargonii strain 305

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag PML25_RS21685 Protein ID WP_168959041.1
Coordinates 5140411..5140692 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PML25_RS21680 Protein ID WP_168959042.1
Coordinates 5140103..5140393 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML25_RS21650 (PML25_21650) 5135277..5135609 + 333 WP_168959046.1 hypothetical protein -
PML25_RS21655 (PML25_21655) 5135724..5136878 - 1155 WP_233366566.1 hypothetical protein -
PML25_RS21660 (PML25_21660) 5136913..5137320 - 408 WP_168959045.1 hypothetical protein -
PML25_RS21665 (PML25_21665) 5137734..5137924 + 191 Protein_4234 hypothetical protein -
PML25_RS21670 (PML25_21670) 5138200..5139018 - 819 WP_218974083.1 AraC family transcriptional regulator -
PML25_RS21675 (PML25_21675) 5139237..5139980 + 744 WP_168959043.1 SDR family oxidoreductase -
PML25_RS21680 (PML25_21680) 5140103..5140393 - 291 WP_168959042.1 HigA family addiction module antitoxin Antitoxin
PML25_RS21685 (PML25_21685) 5140411..5140692 - 282 WP_168959041.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PML25_RS21690 (PML25_21690) 5140904..5141959 - 1056 WP_168959040.1 virulence RhuM family protein -
PML25_RS21695 (PML25_21695) 5142098..5144506 - 2409 WP_168959039.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11056.76 Da        Isoelectric Point: 9.7972

>T269096 WP_168959041.1 NZ_CP116672:c5140692-5140411 [Xanthomonas hortorum pv. pelargonii]
MIRSFVDKEAEKIWLGERSRRLPADIQPVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQWRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10496.19 Da        Isoelectric Point: 7.2043

>AT269096 WP_168959042.1 NZ_CP116672:c5140393-5140103 [Xanthomonas hortorum pv. pelargonii]
MTVLPNIHPGEILLEEFLEPMGISQNALARATAVPPRRINEIVLGKRGITADTAVRLAAALGTTERFWLGLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References