Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3904067..3904569 Replicon chromosome
Accession NZ_CP116621
Organism Proteus terrae strain TP22

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ONR67_RS17960 Protein ID WP_075671248.1
Coordinates 3904315..3904569 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag ONR67_RS17955 Protein ID WP_072068851.1
Coordinates 3904067..3904318 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR67_RS17930 (ONR67_17930) 3899658..3900434 + 777 WP_006534565.1 phosphate ABC transporter ATP-binding protein PstB -
ONR67_RS17935 (ONR67_17935) 3900449..3901183 + 735 WP_075671254.1 phosphate signaling complex protein PhoU -
ONR67_RS17940 (ONR67_17940) 3901399..3902238 + 840 WP_036933789.1 ABC transporter substrate-binding protein -
ONR67_RS17945 (ONR67_17945) 3902345..3903082 + 738 WP_075671252.1 amino acid ABC transporter permease -
ONR67_RS17950 (ONR67_17950) 3903084..3903836 + 753 WP_075671250.1 amino acid ABC transporter permease -
ONR67_RS17955 (ONR67_17955) 3904067..3904318 + 252 WP_072068851.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
ONR67_RS17960 (ONR67_17960) 3904315..3904569 + 255 WP_075671248.1 Txe/YoeB family addiction module toxin Toxin
ONR67_RS17965 (ONR67_17965) 3904726..3906084 + 1359 WP_075671246.1 NCS2 family permease -
ONR67_RS17970 (ONR67_17970) 3906165..3906476 + 312 WP_098941657.1 monooxygenase -
ONR67_RS17975 (ONR67_17975) 3906526..3907074 - 549 WP_109419323.1 GNAT family N-acetyltransferase -
ONR67_RS17980 (ONR67_17980) 3907077..3908549 - 1473 WP_075671240.1 glycosyltransferase family 39 protein -
ONR67_RS17985 (ONR67_17985) 3908738..3909235 + 498 WP_075671238.1 Der GTPase-activating protein YihI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10170.78 Da        Isoelectric Point: 9.9411

>T269090 WP_075671248.1 NZ_CP116621:3904315-3904569 [Proteus terrae]
MKLIFSEQSWSDYLYWQQIDKKIIKRINELIKDIKRTPFSGIGKPEPLKHNLAGFWSRRITDEHRLIYRITDSAIEIASC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9463.77 Da        Isoelectric Point: 4.4354

>AT269090 WP_072068851.1 NZ_CP116621:3904067-3904318 [Proteus terrae]
MKTINYTEARQNLTSIMNETIDDRVPIMITRQKGIPCVLLSLDEYQALEETAYLLRSPANARHLLDSIDELNQGKGIEKD
ITE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References