Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3572980..3573795 Replicon chromosome
Accession NZ_CP116621
Organism Proteus terrae strain TP22

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag ONR67_RS16535 Protein ID WP_075673429.1
Coordinates 3573322..3573795 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag ONR67_RS16530 Protein ID WP_075673430.1
Coordinates 3572980..3573315 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR67_RS16510 (ONR67_16510) 3568669..3570093 + 1425 WP_072069056.1 aspartate ammonia-lyase -
ONR67_RS16515 (ONR67_16515) 3570252..3571577 + 1326 WP_036934359.1 anaerobic C4-dicarboxylate transporter -
ONR67_RS16520 (ONR67_16520) 3571761..3572333 + 573 WP_075673431.1 transcriptional regulator -
ONR67_RS16530 (ONR67_16530) 3572980..3573315 + 336 WP_075673430.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
ONR67_RS16535 (ONR67_16535) 3573322..3573795 + 474 WP_075673429.1 type II toxin-antitoxin system YhaV family toxin Toxin
ONR67_RS16540 (ONR67_16540) 3574106..3574753 + 648 WP_075673428.1 type II CAAX endopeptidase family protein -
ONR67_RS16545 (ONR67_16545) 3575056..3575691 + 636 WP_075673427.1 DUF1449 family protein -
ONR67_RS16550 (ONR67_16550) 3575778..3577973 + 2196 WP_099659727.1 flotillin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(15-109)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18639.26 Da        Isoelectric Point: 9.2715

>T269088 WP_075673429.1 NZ_CP116621:3573322-3573795 [Proteus terrae]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12312.67 Da        Isoelectric Point: 4.2560

>AT269088 WP_075673430.1 NZ_CP116621:3572980-3573315 [Proteus terrae]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References