Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3825973..3826475 Replicon chromosome
Accession NZ_CP116620
Organism Proteus terrae strain CZP50

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ONR71_RS17620 Protein ID WP_075671248.1
Coordinates 3826221..3826475 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag ONR71_RS17615 Protein ID WP_072068851.1
Coordinates 3825973..3826224 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR71_RS17590 (ONR71_17590) 3821564..3822340 + 777 WP_006534565.1 phosphate ABC transporter ATP-binding protein PstB -
ONR71_RS17595 (ONR71_17595) 3822355..3823089 + 735 WP_075671254.1 phosphate signaling complex protein PhoU -
ONR71_RS17600 (ONR71_17600) 3823305..3824144 + 840 WP_036933789.1 ABC transporter substrate-binding protein -
ONR71_RS17605 (ONR71_17605) 3824251..3824988 + 738 WP_075671252.1 amino acid ABC transporter permease -
ONR71_RS17610 (ONR71_17610) 3824990..3825742 + 753 WP_159242128.1 amino acid ABC transporter permease -
ONR71_RS17615 (ONR71_17615) 3825973..3826224 + 252 WP_072068851.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
ONR71_RS17620 (ONR71_17620) 3826221..3826475 + 255 WP_075671248.1 Txe/YoeB family addiction module toxin Toxin
ONR71_RS17625 (ONR71_17625) 3826632..3827990 + 1359 WP_075671246.1 NCS2 family permease -
ONR71_RS17630 (ONR71_17630) 3828071..3828382 + 312 WP_075671244.1 monooxygenase -
ONR71_RS17635 (ONR71_17635) 3828432..3828980 - 549 WP_075671242.1 GNAT family N-acetyltransferase -
ONR71_RS17640 (ONR71_17640) 3828983..3830455 - 1473 WP_075671240.1 glycosyltransferase family 39 protein -
ONR71_RS17645 (ONR71_17645) 3830644..3831141 + 498 WP_075671238.1 Der GTPase-activating protein YihI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10170.78 Da        Isoelectric Point: 9.9411

>T269084 WP_075671248.1 NZ_CP116620:3826221-3826475 [Proteus terrae]
MKLIFSEQSWSDYLYWQQIDKKIIKRINELIKDIKRTPFSGIGKPEPLKHNLAGFWSRRITDEHRLIYRITDSAIEIASC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9463.77 Da        Isoelectric Point: 4.4354

>AT269084 WP_072068851.1 NZ_CP116620:3825973-3826224 [Proteus terrae]
MKTINYTEARQNLTSIMNETIDDRVPIMITRQKGIPCVLLSLDEYQALEETAYLLRSPANARHLLDSIDELNQGKGIEKD
ITE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References