Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3501228..3502043 Replicon chromosome
Accession NZ_CP116620
Organism Proteus terrae strain CZP50

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag ONR71_RS16195 Protein ID WP_075673429.1
Coordinates 3501570..3502043 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag ONR71_RS16190 Protein ID WP_075673430.1
Coordinates 3501228..3501563 (+) Length 112 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR71_RS16170 (ONR71_16170) 3496917..3498341 + 1425 WP_072069056.1 aspartate ammonia-lyase -
ONR71_RS16175 (ONR71_16175) 3498500..3499825 + 1326 WP_036934359.1 anaerobic C4-dicarboxylate transporter -
ONR71_RS16180 (ONR71_16180) 3500009..3500581 + 573 WP_075673431.1 transcriptional regulator -
ONR71_RS16190 (ONR71_16190) 3501228..3501563 + 336 WP_075673430.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
ONR71_RS16195 (ONR71_16195) 3501570..3502043 + 474 WP_075673429.1 type II toxin-antitoxin system YhaV family toxin Toxin
ONR71_RS16200 (ONR71_16200) 3502354..3503001 + 648 WP_075673428.1 type II CAAX endopeptidase family protein -
ONR71_RS16205 (ONR71_16205) 3503304..3503939 + 636 WP_156734149.1 DUF1449 family protein -
ONR71_RS16210 (ONR71_16210) 3504026..3506221 + 2196 WP_099659727.1 flotillin family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(12-147)

Antitoxin

(15-109)


Sequences


Toxin        


Download         Length: 158 a.a.        Molecular weight: 18639.26 Da        Isoelectric Point: 9.2715

>T269082 WP_075673429.1 NZ_CP116620:3501570-3502043 [Proteus terrae]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp


Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12312.67 Da        Isoelectric Point: 4.2560

>AT269082 WP_075673430.1 NZ_CP116620:3501228-3501563 [Proteus terrae]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References