Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2771252..2771523 Replicon chromosome
Accession NZ_CP116575
Organism Enterococcus faecalis strain K205-3

Toxin (Protein)


Gene name txpA Uniprot ID A0A3N3Z2N6
Locus tag PML83_RS13595 Protein ID WP_073340360.1
Coordinates 2771252..2771392 (+) Length 47 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2771325..2771523 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML83_RS13575 2766466..2767458 + 993 WP_002354765.1 biotin--[acetyl-CoA-carboxylase] ligase -
PML83_RS13580 2767722..2768351 - 630 WP_002354763.1 lytic polysaccharide monooxygenase -
PML83_RS13585 2769044..2770660 + 1617 WP_002381036.1 phosphatase PAP2/LCP family protein -
PML83_RS13590 2770990..2771133 + 144 WP_002392818.1 type I toxin-antitoxin system toxin PepG1 -
PML83_RS13595 2771252..2771392 + 141 WP_073340360.1 putative holin-like toxin Toxin
- 2771325..2771523 - 199 - - Antitoxin
PML83_RS13600 2771621..2771764 + 144 WP_002381035.1 putative holin-like toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-46)


Sequences

Toxin        


Download         Length: 47 a.a.        Molecular weight: 5218.33 Da        Isoelectric Point: 10.3265

>T269042 WP_073340360.1 NZ_CP116575:2771252-2771392 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 141 bp

Antitoxin


Download         Length: 199 bp

>AT269042 NZ_CP116575:c2771523-2771325 [Enterococcus faecalis]
TTTTTAGGTAATTGTGCTATAATGGTAATGAAAAGAGAGCTATGCTGTAACATACCTCTCTGATGTAGAGCCGTTTAAGA
CGGTGACCTTTTTGATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATT
TCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3N3Z2N6

Antitoxin

Download structure file

References