Detailed information of TA system TA269029

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 633433..633561
• Replicon: chromosome
• Accession: NZ_CP116575
• Organism: Enterococcus faecalis strain K205-3

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: PML83_RS03240
• Protein ID: WP_271850507.1
• Coordinates: 633433..633561 (+)
• Length: 43 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	633460..633538 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PML83_RS03230	628871..631129	+	2259	WP_002381251.1	DNA helicase PcrA	-
PML83_RS03235	631255..633285	+	2031	WP_002381252.1	NAD-dependent DNA ligase LigA	-
PML83_RS03240	633433..633561	+	129	WP_271850507.1	putative holin-like toxin	Toxin
-	633460..633538	-	79	-	-	Antitoxin
PML83_RS03245	633677..634981	+	1305	WP_089202021.1	ISL3 family transposase	-
PML83_RS03250	635401..635706	+	306	WP_002355569.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
PML83_RS03255	635706..637175	+	1470	WP_002358701.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 43 a.a.
• Molecular weight: 4611.61 Da
• Isoelectric Point: 6.0098

>T269029 WP_271850507.1 NZ_CP116575:633433-633561 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNRLYNLKD

Nucleotide

• Length: 129 bp

Antitoxin

Nucleotide

• Length: 79 bp

>AT269029 NZ_CP116575:c633538-633460 [Enterococcus faecalis]
TATTTTTGTTGTCTAAGACAAGCGCTAAGATACCGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Structures

Antitoxin