Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 609993..610225 Replicon chromosome
Accession NZ_CP116571
Organism Enterococcus faecalis strain K190-1

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag PML73_RS03190 Protein ID WP_033606579.1
Coordinates 609993..610109 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 610020..610225 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML73_RS03180 605431..607689 + 2259 WP_002363179.1 DNA helicase PcrA -
PML73_RS03185 607815..609845 + 2031 WP_002389576.1 NAD-dependent DNA ligase LigA -
PML73_RS03190 609993..610109 + 117 WP_033606579.1 putative holin-like toxin Toxin
- 610020..610225 - 206 - - Antitoxin
PML73_RS03195 610427..610732 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
PML73_RS03200 610732..612201 + 1470 WP_002368026.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
PML73_RS03205 612201..613631 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
PML73_RS03210 613650..614738 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4073.99 Da        Isoelectric Point: 5.9482

>T269001 WP_033606579.1 NZ_CP116571:609993-610109 [Enterococcus faecalis]
MLLSVEAALGLMISFAILVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT269001 NZ_CP116571:c610225-610020 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTATTGCAAAACTAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References