Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2658020..2658355 Replicon chromosome
Accession NZ_CP116559
Organism Enterococcus faecalis strain K137-1a

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag PML94_RS12595 Protein ID WP_002415596.1
Coordinates 2658020..2658163 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2658305..2658355 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML94_RS12575 (2653088) 2653088..2653303 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
PML94_RS12580 (2653442) 2653442..2654434 + 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
PML94_RS12585 (2654738) 2654738..2655376 - 639 WP_002375448.1 lytic polysaccharide monooxygenase -
PML94_RS12590 (2656063) 2656063..2657679 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
PML94_RS12595 (2658020) 2658020..2658163 + 144 WP_002415596.1 type I toxin-antitoxin system toxin PepG1 Toxin
- (2658096) 2658096..2658354 - 259 NuclAT_3 - -
- (2658305) 2658305..2658355 + 51 NuclAT_13 - Antitoxin
PML94_RS12600 (2658356) 2658356..2662123 - 3768 WP_104807327.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5314.46 Da        Isoelectric Point: 10.6323

>T268910 WP_002415596.1 NZ_CP116559:2658020-2658163 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 144 bp

Antitoxin


Download         Length: 51 bp

>AT268910 NZ_CP116559:2658305-2658355 [Enterococcus faecalis]
AATAAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References