268878

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2662332..2662667 Replicon chromosome
Accession NZ_CP116555
Organism Enterococcus faecalis strain K70-12a

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag PML75_RS12600 Protein ID WP_002415596.1
Coordinates 2662332..2662475 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2662617..2662667 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML75_RS12580 (2657400) 2657400..2657615 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
PML75_RS12585 (2657754) 2657754..2658746 + 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
PML75_RS12590 (2659050) 2659050..2659688 - 639 WP_002375448.1 lytic polysaccharide monooxygenase -
PML75_RS12595 (2660375) 2660375..2661991 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
PML75_RS12600 (2662332) 2662332..2662475 + 144 WP_002415596.1 type I toxin-antitoxin system toxin PepG1 Toxin
- (2662408) 2662408..2662666 - 259 NuclAT_3 - -
- (2662617) 2662617..2662667 + 51 NuclAT_13 - Antitoxin
PML75_RS12605 (2662668) 2662668..2666435 - 3768 WP_104807327.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5314.46 Da        Isoelectric Point: 10.6323

>T268878 WP_002415596.1 NZ_CP116555:2662332-2662475 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 144 bp

Antitoxin


Download         Length: 51 bp

>AT268878 NZ_CP116555:2662617-2662667 [Enterococcus faecalis]
AATAAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References