Detailed information of TA system TA268869

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2583511..2583735
• Replicon: chromosome
• Accession: NZ_CP116555
• Organism: Enterococcus faecalis strain K70-12a

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: PML75_RS12250
• Protein ID: WP_023894767.1
• Coordinates: 2583631..2583735 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2583511..2583698 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PML75_RS12235 (2578880)	2578880..2579593	-	714	WP_002367455.1	trehalose operon repressor	-
PML75_RS12240 (2579854)	2579854..2582598	+	2745	WP_104807179.1	glycosyl hydrolase family 65 protein	-
PML75_RS12245 (2582613)	2582613..2583263	+	651	WP_002375514.1	beta-phosphoglucomutase	-
- (2583332)	2583332..2583464	+	133	NuclAT_12	-	-
- (2583511)	2583511..2583698	+	188	NuclAT_4	-	Antitoxin
PML75_RS12250 (2583631)	2583631..2583735	-	105	WP_023894767.1	putative holin-like toxin	Toxin
- (2583887)	2583887..2584032	+	146	NuclAT_11	-	-
- (2583887)	2583887..2584073	+	187	NuclAT_5	-	-
PML75_RS12255 (2584006)	2584006..2584158	-	153	WP_002375510.1	type I toxin-antitoxin system toxin PepG1	-
PML75_RS12260 (2584383)	2584383..2585354	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
PML75_RS12265 (2585529)	2585529..2585966	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
PML75_RS12270 (2586099)	2586099..2586653	-	555	WP_002354869.1	Maf family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3799.63 Da
• Isoelectric Point: 10.0079

>T268869 WP_023894767.1 NZ_CP116555:c2583735-2583631 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 188 bp

>AT268869 NZ_CP116555:2583511-2583698 [Enterococcus faecalis]
TGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACTTTTT
GAATTATTTAAAAATAACCGTACTCGGTCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAAGCAATTTAACAATCAGC
GCAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin