Detailed information of TA system TA268860

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2622090..2622424
• Replicon: chromosome
• Accession: NZ_CP116553
• Organism: Enterococcus faecalis strain K80-2b

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: PML81_RS12290
• Protein ID: WP_002415596.1
• Coordinates: 2622090..2622233 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2622166..2622424 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PML81_RS12270 (2617158)	2617158..2617373	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
PML81_RS12275 (2617512)	2617512..2618504	+	993	WP_002358973.1	biotin--[acetyl-CoA-carboxylase] ligase	-
PML81_RS12280 (2618808)	2618808..2619446	-	639	WP_002375448.1	lytic polysaccharide monooxygenase	-
PML81_RS12285 (2620133)	2620133..2621749	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
PML81_RS12290 (2622090)	2622090..2622233	+	144	WP_002415596.1	type I toxin-antitoxin system toxin PepG1	Toxin
- (2622166)	2622166..2622424	-	259	NuclAT_3	-	Antitoxin
- (2622375)	2622375..2622425	+	51	NuclAT_13	-	-
PML81_RS12295 (2622426)	2622426..2626193	-	3768	WP_104807327.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5314.46 Da
• Isoelectric Point: 10.6323

>T268860 WP_002415596.1 NZ_CP116553:2622090-2622233 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 259 bp

>AT268860 NZ_CP116553:c2622424-2622166 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAA
TGATAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTACTT
AAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAA
GCAATGGTAAACATACCAA

Structures

Antitoxin