Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
Location | 155138..155673 | Replicon | plasmid pK80-15b-A |
Accession | NZ_CP116550 | ||
Organism | Enterococcus faecium strain K80-15b |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | R2PQC0 |
Locus tag | PML85_RS13715 | Protein ID | WP_002314366.1 |
Coordinates | 155138..155410 (-) | Length | 91 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | Q3Y220 |
Locus tag | PML85_RS13720 | Protein ID | WP_002297422.1 |
Coordinates | 155410..155673 (-) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PML85_RS13680 (PML85_13680) | 151396..151548 | + | 153 | Protein_155 | IS6 family transposase | - |
PML85_RS13685 (PML85_13685) | 151582..151755 | - | 174 | WP_229214455.1 | hypothetical protein | - |
PML85_RS13690 (PML85_13690) | 151767..152504 | - | 738 | WP_002331331.1 | S8 family serine peptidase | - |
PML85_RS13695 (PML85_13695) | 152764..153312 | - | 549 | WP_002292681.1 | hypothetical protein | - |
PML85_RS13700 (PML85_13700) | 153313..154170 | - | 858 | WP_002292680.1 | ParA family protein | - |
PML85_RS13705 (PML85_13705) | 154455..154742 | - | 288 | WP_002300557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
PML85_RS13710 (PML85_13710) | 154732..155061 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
PML85_RS13715 (PML85_13715) | 155138..155410 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin |
PML85_RS13720 (PML85_13720) | 155410..155673 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
PML85_RS13725 (PML85_13725) | 155779..156702 | - | 924 | WP_002331332.1 | hypothetical protein | - |
PML85_RS13730 (PML85_13730) | 157261..157578 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
PML85_RS13735 (PML85_13735) | 157579..157833 | - | 255 | WP_002297424.1 | hypothetical protein | - |
PML85_RS13740 (PML85_13740) | 158093..158233 | - | 141 | WP_002290398.1 | hypothetical protein | - |
PML85_RS13745 (PML85_13745) | 158871..158957 | - | 87 | Protein_168 | single-stranded DNA-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..160122 | 160122 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829F704 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829F006 |