Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 378371..379095 | Replicon | chromosome |
Accession | NZ_CP116477 | ||
Organism | Pectobacterium sp. A5351 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | O1Q74_RS01775 | Protein ID | WP_271875839.1 |
Coordinates | 378371..378682 (+) | Length | 104 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | O1Q74_RS01780 | Protein ID | WP_271875840.1 |
Coordinates | 378679..379095 (+) | Length | 139 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
O1Q74_RS01760 (O1Q74_01760) | 374531..376066 | - | 1536 | WP_271875836.1 | carbohydrate porin | - |
O1Q74_RS01765 (O1Q74_01765) | 376255..377190 | - | 936 | WP_271875837.1 | aminoimidazole riboside kinase | - |
O1Q74_RS01770 (O1Q74_01770) | 377661..378212 | + | 552 | WP_271875838.1 | polymer-forming cytoskeletal protein | - |
O1Q74_RS01775 (O1Q74_01775) | 378371..378682 | + | 312 | WP_271875839.1 | type II toxin-antitoxin system HigB family toxin | Toxin |
O1Q74_RS01780 (O1Q74_01780) | 378679..379095 | + | 417 | WP_271875840.1 | helix-turn-helix domain-containing protein | Antitoxin |
O1Q74_RS01785 (O1Q74_01785) | 379443..379889 | + | 447 | WP_271875841.1 | helix-turn-helix domain-containing protein | - |
O1Q74_RS01790 (O1Q74_01790) | 379899..380360 | + | 462 | WP_271875842.1 | YhbP family protein | - |
O1Q74_RS01795 (O1Q74_01795) | 380454..381107 | + | 654 | WP_271875843.1 | hypothetical protein | - |
O1Q74_RS01800 (O1Q74_01800) | 381119..381583 | - | 465 | WP_271875844.1 | anaerobic ribonucleoside-triphosphate reductase-activating protein | - |
O1Q74_RS01805 (O1Q74_01805) | 381665..383803 | - | 2139 | WP_271875845.1 | anaerobic ribonucleoside-triphosphate reductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 a.a. Molecular weight: 12439.28 Da Isoelectric Point: 9.6392
>T268716 WP_271875839.1 NZ_CP116477:378371-378682 [Pectobacterium sp. A5351]
MHVISRAPFDTATTQFPNQAAALADLYRVIKREMYATPDDMKKRFPSLDRMKYREKWWVIDIGGGHLRMMFFADFERGEI
FIKHITSHAEYDRLTEYYRRNKE
MHVISRAPFDTATTQFPNQAAALADLYRVIKREMYATPDDMKKRFPSLDRMKYREKWWVIDIGGGHLRMMFFADFERGEI
FIKHITSHAEYDRLTEYYRRNKE
Download Length: 312 bp
Antitoxin
Download Length: 139 a.a. Molecular weight: 15412.67 Da Isoelectric Point: 4.5581
>AT268716 WP_271875840.1 NZ_CP116477:378679-379095 [Pectobacterium sp. A5351]
MMYADAIKAANNLMSIVPFLGGSTSRKDYEDALKLTEYLIESEPDSPLIDMLTAKIDKYEDDASEFAAFNERVKALPAGI
ALLRVLMDQHQLTQSDFEAEIGKKSLVSRILNGERTLTLDHMRALAKRFDIPVSAFVD
MMYADAIKAANNLMSIVPFLGGSTSRKDYEDALKLTEYLIESEPDSPLIDMLTAKIDKYEDDASEFAAFNERVKALPAGI
ALLRVLMDQHQLTQSDFEAEIGKKSLVSRILNGERTLTLDHMRALAKRFDIPVSAFVD
Download Length: 417 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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