Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 31943..32615 Replicon chromosome
Accession NZ_CP116477
Organism Pectobacterium sp. A5351

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag O1Q74_RS00190 Protein ID WP_271875380.1
Coordinates 32229..32615 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag O1Q74_RS00185 Protein ID WP_180779427.1
Coordinates 31943..32242 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q74_RS00165 (O1Q74_00165) 27196..28185 + 990 WP_271875371.1 nucleoside hydrolase -
O1Q74_RS00170 (O1Q74_00170) 28185..29162 + 978 WP_271875373.1 ABC transporter permease -
O1Q74_RS00175 (O1Q74_00175) 29159..30067 + 909 WP_271875375.1 ABC transporter permease -
O1Q74_RS00180 (O1Q74_00180) 30107..31906 + 1800 WP_271875376.1 ABC transporter ATP-binding protein -
O1Q74_RS00185 (O1Q74_00185) 31943..32242 - 300 WP_180779427.1 XRE family transcriptional regulator Antitoxin
O1Q74_RS00190 (O1Q74_00190) 32229..32615 - 387 WP_271875380.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O1Q74_RS00195 (O1Q74_00195) 32879..33376 + 498 WP_271875382.1 GNAT family N-acetyltransferase -
O1Q74_RS00200 (O1Q74_00200) 33576..33833 - 258 WP_012772768.1 DUF1471 domain-containing protein -
O1Q74_RS00205 (O1Q74_00205) 34006..34806 - 801 WP_271875385.1 aliphatic sulfonates ABC transporter ATP-binding protein -
O1Q74_RS00210 (O1Q74_00210) 34803..35597 - 795 WP_271875387.1 aliphatic sulfonate ABC transporter permease SsuC -
O1Q74_RS00215 (O1Q74_00215) 35609..36751 - 1143 WP_271875389.1 FMNH2-dependent alkanesulfonate monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-113)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-80)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14892.88 Da        Isoelectric Point: 4.6333

>T268713 WP_271875380.1 NZ_CP116477:c32615-32229 [Pectobacterium sp. A5351]
MEVYRLAWEIVTRALFDTWFDEQTETVQEEVLAHLGILEEDGPQLGRPQVDQIKGSQYKNMKELRVQVGDHPFRTFFAFD
RTRKAIVLCAGDKKGENEKLFYERMIKIADAEFTSHLISPEVKEDGDI

Download         Length: 387 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11082.10 Da        Isoelectric Point: 10.6442

>AT268713 WP_180779427.1 NZ_CP116477:c32242-31943 [Pectobacterium sp. A5351]
MATFKEMMAKRSPESRARIEARTAEIRQEITLAKLREELNMSQTQLALALGVKQPSIVKMEKVENDPKLSTLKRYVTALG
GKLTLDVTLPDGKRIALTL

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References