Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsA(antitoxin)
Location 1845719..1846311 Replicon chromosome
Accession NZ_CP116458
Organism Acidithiobacillus ferriphilus strain YL25

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag PJU76_RS09305 Protein ID WP_271779301.1
Coordinates 1846129..1846311 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag PJU76_RS09300 Protein ID WP_271779300.1
Coordinates 1845719..1846126 (-) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJU76_RS09285 (PJU76_09285) 1841451..1842563 - 1113 WP_271779297.1 sigma-54 dependent transcriptional regulator -
PJU76_RS09290 (PJU76_09290) 1842855..1843802 - 948 WP_271779298.1 chemotaxis protein -
PJU76_RS09295 (PJU76_09295) 1843814..1845064 - 1251 WP_271779299.1 methyl-accepting chemotaxis protein -
PJU76_RS09300 (PJU76_09300) 1845719..1846126 - 408 WP_271779300.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PJU76_RS09305 (PJU76_09305) 1846129..1846311 - 183 WP_271779301.1 hypothetical protein Toxin
PJU76_RS09310 (PJU76_09310) 1846467..1847240 + 774 WP_271779302.1 DUF4113 domain-containing protein -
PJU76_RS09315 (PJU76_09315) 1847514..1848629 + 1116 WP_271779303.1 hypothetical protein -
PJU76_RS09320 (PJU76_09320) 1848795..1849319 + 525 WP_271779304.1 hypothetical protein -
PJU76_RS09325 (PJU76_09325) 1849536..1849844 + 309 WP_271779305.1 roadblock/LC7 domain-containing protein -
PJU76_RS09330 (PJU76_09330) 1849893..1850255 + 363 WP_271779306.1 roadblock/LC7 domain-containing protein -
PJU76_RS09335 (PJU76_09335) 1850422..1850973 + 552 WP_271779307.1 protoglobin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA

(3-130)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6420.67 Da        Isoelectric Point: 9.4060

>T268711 WP_271779301.1 NZ_CP116458:c1846311-1846129 [Acidithiobacillus ferriphilus]
MEKGILHCKLATVKALTEAGKVNTTASAFKGARELGINDLAGMCTMPRQITVLIVSFKEL

Download         Length: 183 bp

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 14917.17 Da        Isoelectric Point: 8.0216

>AT268711 WP_271779300.1 NZ_CP116458:c1846126-1845719 [Acidithiobacillus ferriphilus]
MKCPCCGVAELIHDTRDMPYIYKGETTTIPAVTGDFCPACGEVVLNREYGGRYSELIGQFQRQVNSAYVDPHYIALVRKK
LDLDQRQAAAIFGGGANAFSRYENGKTKPSLALVKLLKVLERHPDLLNEVKSGPV

Download         Length: 408 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References