268582

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3552830..3553523 Replicon chromosome
Accession NZ_CP116304
Organism Pseudomonas sp. Q1-7

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PJW05_RS16365 Protein ID WP_271408051.1
Coordinates 3552830..3553114 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PJW05_RS16370 Protein ID WP_271408052.1
Coordinates 3553122..3553523 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJW05_RS16350 3548658..3549461 - 804 Protein_3214 NYN domain-containing protein -
PJW05_RS16355 3549791..3551731 + 1941 WP_271408050.1 aconitate hydratase -
PJW05_RS16360 3552122..3552617 + 496 Protein_3216 type IV secretory system conjugative DNA transfer family protein -
PJW05_RS16365 3552830..3553114 + 285 WP_271408051.1 type II toxin-antitoxin system HigB family toxin Toxin
PJW05_RS16370 3553122..3553523 + 402 WP_271408052.1 helix-turn-helix domain-containing protein Antitoxin
PJW05_RS16375 3553585..3553746 + 162 WP_271408053.1 type II toxin-antitoxin system MqsA family antitoxin -
PJW05_RS16380 3554342..3555498 + 1157 WP_271408054.1 IS3 family transposase -
PJW05_RS16385 3555826..3556122 + 297 WP_271408055.1 helix-turn-helix transcriptional regulator -
PJW05_RS16390 3556294..3556578 + 285 WP_271408056.1 pyocin activator PrtN family protein -
PJW05_RS16395 3556544..3557695 - 1152 WP_271408057.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3537647..3571916 34269


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(78-132)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11273.10 Da        Isoelectric Point: 10.1824

>T268582 WP_271408051.1 NZ_CP116304:3552830-3553114 [Pseudomonas sp. Q1-7]
MHIITQKRIWEAKEKWPHAATALDAWYRLMSKLEPRDFADMKQTFPSVDKVADKHVFDIGGNKLRLIAVVDYQFKKVFIR
AVLDHKEYDRNQWK

Download         Length: 285 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14748.73 Da        Isoelectric Point: 4.7411

>AT268582 WP_271408052.1 NZ_CP116304:3553122-3553523 [Pseudomonas sp. Q1-7]
MSALLKQAVAHWRYVAPLLTPPQNEADYDALVEALDELLDEVAGIENHPLSALASQMGDLIAAYDAHHYAIPEAPGHEVL
RYLMSEHNLTQSDLPEIGAQSVVSEILNGKRQLNVRHIRALAERFKVPADVFF

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References