268566

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 6132773..6133287 Replicon chromosome
Accession NZ_CP116257
Organism Streptomyces lienomycini strain DSM 41475

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BJ961_RS27960 Protein ID WP_134655433.1
Coordinates 6133033..6133287 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BJ961_RS27955 Protein ID WP_271415559.1
Coordinates 6132773..6133036 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJ961_RS27945 6128657..6129517 + 861 WP_271415557.1 phosphatase PAP2 family protein -
BJ961_RS27950 6129597..6132599 - 3003 WP_271415558.1 bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase -
BJ961_RS27955 6132773..6133036 + 264 WP_271415559.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BJ961_RS27960 6133033..6133287 + 255 WP_134655433.1 Txe/YoeB family addiction module toxin Toxin
BJ961_RS27965 6133281..6135095 - 1815 WP_271415560.1 NAD+ synthase -
BJ961_RS27970 6135179..6135805 - 627 WP_271415561.1 DUF305 domain-containing protein -
BJ961_RS27975 6135802..6136476 - 675 WP_271415562.1 DUF3105 domain-containing protein -
BJ961_RS27980 6136780..6138141 + 1362 WP_052840241.1 type I glutamate--ammonia ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9999.34 Da        Isoelectric Point: 9.7377

>T268566 WP_134655433.1 NZ_CP116257:6133033-6133287 [Streptomyces lienomycini]
VRITFTSHGWEDYVHWAESDRKVTKRINRLISDITRDPFKGIGKPEPLKGDLSGYWSRRIDDTHRLVYKPTDDVLIIVQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9716.81 Da        Isoelectric Point: 5.1167

>AT268566 WP_271415559.1 NZ_CP116257:6132773-6133036 [Streptomyces lienomycini]
MSITASEARQNLFPLIEQVNEDHAPVHITSRKGNAVLMSEEDFTAWTETVHLLRSPRNARRLLDSIAEAEAGGARRHDLI
DPDAERA

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References