268470

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 4153511..4154015 Replicon chromosome
Accession NZ_CP116222
Organism Providencia vermicola strain PVA41-chromosome

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PG365_RS18770 Protein ID WP_282560439.1
Coordinates 4153758..4154015 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PG365_RS18765 Protein ID WP_196714179.1
Coordinates 4153511..4153765 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG365_RS18745 (PG365_18745) 4149183..4149611 + 429 WP_251464799.1 protein tyrosine phosphatase -
PG365_RS18750 (PG365_18750) 4149645..4151723 + 2079 WP_251464800.1 polysaccharide biosynthesis tyrosine autokinase -
PG365_RS18755 (PG365_18755) 4151741..4152766 + 1026 WP_251464801.1 UDP-glucose 4-epimerase GalE -
PG365_RS18760 (PG365_18760) 4152929..4153432 + 504 WP_154624169.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PG365_RS18765 (PG365_18765) 4153511..4153765 + 255 WP_196714179.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PG365_RS18770 (PG365_18770) 4153758..4154015 + 258 WP_282560439.1 Txe/YoeB family addiction module toxin Toxin
PG365_RS18775 (PG365_18775) 4154124..4154945 - 822 WP_154624171.1 serine O-acetyltransferase -
PG365_RS18780 (PG365_18780) 4154971..4155999 - 1029 WP_154624172.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
PG365_RS18785 (PG365_18785) 4156008..4156475 - 468 WP_154624173.1 protein-export chaperone SecB -
PG365_RS18790 (PG365_18790) 4156595..4157032 - 438 WP_154624174.1 rhodanese-like domain-containing protein -
PG365_RS18795 (PG365_18795) 4157529..4158821 + 1293 WP_163863391.1 murein hydrolase activator EnvC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10140.63 Da        Isoelectric Point: 8.8172

>T268470 WP_282560439.1 NZ_CP116222:4153758-4154015 [Providencia vermicola]
MSRFLITDQGWEDYLYRQTQDKKMLKRINKLIDETKRTPFYGIGKPEPLKENLAGFWSRRIDETNRLIYSIDDEGLTIIA
CRYY

Download         Length: 258 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9477.79 Da        Isoelectric Point: 5.8373

>AT268470 WP_196714179.1 NZ_CP116222:4153511-4153765 [Providencia vermicola]
MKTISFSEARNNLKSVLDKVVDDADTTIITPRDSEDAGVMSLEYYNSLMETIYLLRSPANAEHLNKSIAQFKAGKVKKRE
LINE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References