Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RelE-RHH |
Location | 2275..2836 | Replicon | plasmid pDETEC33 |
Accession | NZ_CP116125 | ||
Organism | Escherichia coli strain DETEC-P666 |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | PIB57_RS24400 | Protein ID | WP_013009346.1 |
Coordinates | 2558..2836 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | - |
Locus tag | PIB57_RS24395 | Protein ID | WP_271291420.1 |
Coordinates | 2275..2535 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PIB57_RS24385 (PIB57_24390) | 495..1367 | + | 873 | WP_000729438.1 | incFII family plasmid replication initiator RepA | - |
PIB57_RS24390 (PIB57_24395) | 2062..2220 | + | 159 | WP_000829588.1 | hypothetical protein | - |
PIB57_RS24395 (PIB57_24400) | 2275..2535 | + | 261 | WP_271291420.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin |
PIB57_RS24400 (PIB57_24405) | 2558..2836 | + | 279 | WP_013009346.1 | type II toxin-antitoxin system toxin YacB | Toxin |
PIB57_RS24405 (PIB57_24410) | 3032..3328 | - | 297 | WP_001419651.1 | hypothetical protein | - |
PIB57_RS24410 (PIB57_24415) | 3673..4260 | + | 588 | WP_001418189.1 | serine acetyltransferase | - |
PIB57_RS24415 (PIB57_24420) | 4542..5135 | - | 594 | WP_001401779.1 | ProQ/FINO family protein | - |
PIB57_RS24420 (PIB57_24425) | 5489..6835 | + | 1347 | WP_001132021.1 | protein YagA | - |
PIB57_RS24425 (PIB57_24430) | 7156..7674 | + | 519 | WP_000115885.1 | ClbS/DfsB family four-helix bundle protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | - | - | 1..86916 | 86916 | |
flank | IS/Tn | - | - | 7693..8913 | 1220 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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