Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-as-bsrH/-
Location 2373894..2374111 Replicon chromosome
Accession NZ_CP116012
Organism Bacillus subtilis strain SRCM124333

Toxin (Protein)


Gene name yonT Uniprot ID A0A6H0WKE8
Locus tag PF977_RS12820 Protein ID WP_032721653.1
Coordinates 2373894..2374070 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2374011..2374111 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF977_RS12760 (2368968) 2368968..2369189 - 222 WP_213418992.1 helix-turn-helix transcriptional regulator -
PF977_RS12765 (2369256) 2369256..2369588 - 333 WP_019712280.1 hypothetical protein -
PF977_RS12770 (2369658) 2369658..2369855 - 198 WP_032677195.1 hypothetical protein -
PF977_RS12775 (2369958) 2369958..2370284 - 327 WP_271259403.1 hypothetical protein -
PF977_RS12780 (2370503) 2370503..2370739 - 237 WP_003230991.1 hypothetical protein -
PF977_RS12785 (2370762) 2370762..2370935 - 174 WP_015968356.1 hypothetical protein -
PF977_RS12790 (2370932) 2370932..2371147 - 216 WP_032677193.1 hypothetical protein -
PF977_RS12795 (2371180) 2371180..2371461 - 282 WP_050496376.1 hypothetical protein -
PF977_RS12800 (2371495) 2371495..2371764 - 270 WP_006640590.1 hypothetical protein -
PF977_RS12805 (2372092) 2372092..2373309 - 1218 WP_032721658.1 hypothetical protein -
PF977_RS12810 (2373391) 2373391..2373579 - 189 WP_032721656.1 hypothetical protein -
PF977_RS12815 (2373624) 2373624..2373875 - 252 WP_074794695.1 hypothetical protein -
PF977_RS12820 (2373894) 2373894..2374070 - 177 WP_032721653.1 hypothetical protein Toxin
- (2374011) 2374011..2374111 + 101 NuclAT_0 - Antitoxin
- (2374011) 2374011..2374111 + 101 NuclAT_0 - Antitoxin
- (2374011) 2374011..2374111 + 101 NuclAT_0 - Antitoxin
- (2374011) 2374011..2374111 + 101 NuclAT_0 - Antitoxin
PF977_RS12825 (2374611) 2374611..2375222 - 612 WP_074794693.1 hypothetical protein -
PF977_RS12830 (2375423) 2375423..2375752 - 330 WP_032721651.1 helix-turn-helix transcriptional regulator -
PF977_RS12835 (2376704) 2376704..2376898 + 195 WP_032721649.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2243664..2450695 207031


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 59 a.a.        Molecular weight: 6850.39 Da        Isoelectric Point: 12.8833

>T267624 WP_032721653.1 NZ_CP116012:c2374070-2373894 [Bacillus subtilis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp


Antitoxin


Download         Length: 101 bp

>AT267624 NZ_CP116012:2374011-2374111 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A6H0WKE8


Antitoxin

Download structure file

References