Detailed information of TA system TA267622

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2373853..2374070
• Replicon: chromosome
• Accession: NZ_CP116012
• Organism: Bacillus subtilis strain SRCM124333

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: A0A6H0WKE8
• Locus tag: PF977_RS12820
• Protein ID: WP_032721653.1
• Coordinates: 2373894..2374070 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2373853..2373953 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PF977_RS12760	2368968..2369189	-	222	WP_213418992.1	helix-turn-helix transcriptional regulator	-
PF977_RS12765	2369256..2369588	-	333	WP_019712280.1	hypothetical protein	-
PF977_RS12770	2369658..2369855	-	198	WP_032677195.1	hypothetical protein	-
PF977_RS12775	2369958..2370284	-	327	WP_271259403.1	hypothetical protein	-
PF977_RS12780	2370503..2370739	-	237	WP_003230991.1	hypothetical protein	-
PF977_RS12785	2370762..2370935	-	174	WP_015968356.1	hypothetical protein	-
PF977_RS12790	2370932..2371147	-	216	WP_032677193.1	hypothetical protein	-
PF977_RS12795	2371180..2371461	-	282	WP_050496376.1	hypothetical protein	-
PF977_RS12800	2371495..2371764	-	270	WP_006640590.1	hypothetical protein	-
PF977_RS12805	2372092..2373309	-	1218	WP_032721658.1	hypothetical protein	-
PF977_RS12810	2373391..2373579	-	189	WP_032721656.1	hypothetical protein	-
PF977_RS12815	2373624..2373875	-	252	WP_074794695.1	hypothetical protein	-
-	2373853..2373953	+	101	-	-	Antitoxin
PF977_RS12820	2373894..2374070	-	177	WP_032721653.1	hypothetical protein	Toxin
-	2374011..2374111	+	101	NuclAT_0	-	-
-	2374011..2374111	+	101	NuclAT_0	-	-
-	2374011..2374111	+	101	NuclAT_0	-	-
-	2374011..2374111	+	101	NuclAT_0	-	-
PF977_RS12825	2374611..2375222	-	612	WP_074794693.1	hypothetical protein	-
PF977_RS12830	2375423..2375752	-	330	WP_032721651.1	helix-turn-helix transcriptional regulator	-
PF977_RS12835	2376704..2376898	+	195	WP_032721649.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2243664..2450695	207031

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6850.39 Da
• Isoelectric Point: 12.8833

>T267622 WP_032721653.1 NZ_CP116012:c2374070-2373894 [Bacillus subtilis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 101 bp

>AT267622 NZ_CP116012:2373853-2373953 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: A0A6H0WKE8

Antitoxin