Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | yonT-as-bsrH/- |
| Location | 2373624..2374111 | Replicon | chromosome |
| Accession | NZ_CP116012 | ||
| Organism | Bacillus subtilis strain SRCM124333 | ||
Toxin (Protein)
| Gene name | yonT | Uniprot ID | A0A8E0VV64 |
| Locus tag | PF977_RS12815 | Protein ID | WP_074794695.1 |
| Coordinates | 2373624..2373875 (-) | Length | 84 a.a. |
Antitoxin (RNA)
| Gene name | as-bsrH | ||
| Locus tag | - | ||
| Coordinates | 2374011..2374111 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PF977_RS12755 (2368662) | 2368662..2368895 | - | 234 | WP_213418978.1 | hypothetical protein | - |
| PF977_RS12760 (2368968) | 2368968..2369189 | - | 222 | WP_213418992.1 | helix-turn-helix transcriptional regulator | - |
| PF977_RS12765 (2369256) | 2369256..2369588 | - | 333 | WP_019712280.1 | hypothetical protein | - |
| PF977_RS12770 (2369658) | 2369658..2369855 | - | 198 | WP_032677195.1 | hypothetical protein | - |
| PF977_RS12775 (2369958) | 2369958..2370284 | - | 327 | WP_271259403.1 | hypothetical protein | - |
| PF977_RS12780 (2370503) | 2370503..2370739 | - | 237 | WP_003230991.1 | hypothetical protein | - |
| PF977_RS12785 (2370762) | 2370762..2370935 | - | 174 | WP_015968356.1 | hypothetical protein | - |
| PF977_RS12790 (2370932) | 2370932..2371147 | - | 216 | WP_032677193.1 | hypothetical protein | - |
| PF977_RS12795 (2371180) | 2371180..2371461 | - | 282 | WP_050496376.1 | hypothetical protein | - |
| PF977_RS12800 (2371495) | 2371495..2371764 | - | 270 | WP_006640590.1 | hypothetical protein | - |
| PF977_RS12805 (2372092) | 2372092..2373309 | - | 1218 | WP_032721658.1 | hypothetical protein | - |
| PF977_RS12810 (2373391) | 2373391..2373579 | - | 189 | WP_032721656.1 | hypothetical protein | - |
| PF977_RS12815 (2373624) | 2373624..2373875 | - | 252 | WP_074794695.1 | hypothetical protein | Toxin |
| PF977_RS12820 (2373894) | 2373894..2374070 | - | 177 | WP_032721653.1 | hypothetical protein | - |
| - (2374011) | 2374011..2374111 | + | 101 | NuclAT_0 | - | Antitoxin |
| - (2374011) | 2374011..2374111 | + | 101 | NuclAT_0 | - | Antitoxin |
| - (2374011) | 2374011..2374111 | + | 101 | NuclAT_0 | - | Antitoxin |
| - (2374011) | 2374011..2374111 | + | 101 | NuclAT_0 | - | Antitoxin |
| PF977_RS12825 (2374611) | 2374611..2375222 | - | 612 | WP_074794693.1 | hypothetical protein | - |
| PF977_RS12830 (2375423) | 2375423..2375752 | - | 330 | WP_032721651.1 | helix-turn-helix transcriptional regulator | - |
| PF977_RS12835 (2376704) | 2376704..2376898 | + | 195 | WP_032721649.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2243664..2450695 | 207031 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 84 a.a. Molecular weight: 10099.18 Da Isoelectric Point: 10.0301
>T267621 WP_074794695.1 NZ_CP116012:c2373875-2373624 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIVNMKRFSLWFTHITFIGLFLMFQLIKDYFSSEAQTLINIIFIVTCIIAILLWIIYFVFLKLRN
KSH
MNFSFSSYPYYNMIKHIVNMKRFSLWFTHITFIGLFLMFQLIKDYFSSEAQTLINIIFIVTCIIAILLWIIYFVFLKLRN
KSH
Download Length: 252 bp
Antitoxin
Download Length: 101 bp
>AT267621 NZ_CP116012:2374011-2374111 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
