Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 887084..887925 Replicon plasmid pmega
Accession NZ_CP115956
Organism Ralstonia pseudosolanacearum strain RUN2340

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag PG907_RS21570 Protein ID WP_197366231.1
Coordinates 887084..887599 (-) Length 172 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag PG907_RS21575 Protein ID WP_193028732.1
Coordinates 887596..887925 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG907_RS21555 883166..884044 - 879 WP_193028734.1 EamA family transporter -
PG907_RS21560 884282..885178 - 897 WP_043899999.1 LysR substrate-binding domain-containing protein -
PG907_RS21565 885311..886639 - 1329 WP_193027137.1 IS4 family transposase -
PG907_RS21570 887084..887599 - 516 WP_197366231.1 type II toxin-antitoxin system YhaV family toxin Toxin
PG907_RS21575 887596..887925 - 330 WP_193028732.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
PG907_RS21585 889065..889271 + 207 Protein_735 JAB domain-containing protein -
PG907_RS21590 889330..890511 + 1182 WP_193028729.1 PDDEXK nuclease domain-containing protein -
PG907_RS21595 890666..891526 - 861 WP_197366230.1 spermidine synthase -
PG907_RS21600 891830..892765 + 936 WP_193037658.1 5-dehydro-4-deoxyglucarate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..1973144 1973144
- flank IS/Tn - - 885311..886639 1328


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 19671.40 Da        Isoelectric Point: 9.6724

>T267549 WP_197366231.1 NZ_CP115956:c887599-887084 [Ralstonia pseudosolanacearum]
MTAVQPVPLVIHGWTIFAHPLLLDQLDALTRQVEAQREKDPTGYVKKNATKRLAAICKLAFDVIPQDPARPEYRQGHTLG
DENKHWFRAKFFQQYRLFFRFHAPSKMIVLAWINDADTKRAYESDDDAYRVFKRMLASGHPPNDWEPLLTEASRQSERLQ
STAGALGTGHR

Download         Length: 516 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12110.59 Da        Isoelectric Point: 4.4731

>AT267549 WP_193028732.1 NZ_CP115956:c887925-887596 [Ralstonia pseudosolanacearum]
MPVTLEAESTLTDRYQTTVPETVRRALRLGKRDKIHYTIRQTGEVVLTRADDDEAADPVLGQFLRFLAQDIAAHPERLQG
LDTSLVQRIHTLVGGIEVDLDAALSADDE

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References