Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2272026..2272532 Replicon chromosome
Accession NZ_CP115917
Organism Tenacibaculum pacificus strain 18-2881-A

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PG913_RS10355 Protein ID WP_271230639.1
Coordinates 2272026..2272283 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PG913_RS10360 Protein ID WP_214983341.1
Coordinates 2272284..2272532 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG913_RS10325 (PG913_10325) 2267617..2268729 + 1113 WP_271230634.1 HAMP domain-containing sensor histidine kinase -
PG913_RS10330 (PG913_10330) 2268744..2269136 - 393 WP_271230635.1 HIT family protein -
PG913_RS10335 (PG913_10335) 2269229..2269702 - 474 WP_271230636.1 transcription elongation factor GreA -
PG913_RS10340 (PG913_10340) 2269809..2270219 + 411 WP_271230637.1 Rieske 2Fe-2S domain-containing protein -
PG913_RS10345 (PG913_10345) 2270286..2271443 + 1158 WP_271230638.1 5-(carboxyamino)imidazole ribonucleotide synthase -
PG913_RS10350 (PG913_10350) 2271487..2271966 + 480 WP_214984972.1 5-(carboxyamino)imidazole ribonucleotide mutase -
PG913_RS10355 (PG913_10355) 2272026..2272283 - 258 WP_271230639.1 Txe/YoeB family addiction module toxin Toxin
PG913_RS10360 (PG913_10360) 2272284..2272532 - 249 WP_214983341.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PG913_RS10365 (PG913_10365) 2272659..2274677 + 2019 WP_271230640.1 M3 family metallopeptidase -
PG913_RS10370 (PG913_10370) 2274760..2275980 + 1221 WP_271230641.1 carboxypeptidase-like regulatory domain-containing protein -
PG913_RS10375 (PG913_10375) 2275977..2277211 - 1235 Protein_1992 glycosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10375.00 Da        Isoelectric Point: 9.7876

>T267491 WP_271230639.1 NZ_CP115917:c2272283-2272026 [Tenacibaculum pacificus]
MKLTWSTSSWEDYLYWQKVDKKIVKRINELIKNCMRTPFEGIGKPEALKGDLQGYWSRRITSEHRLVYKYENEQILIAAC
RYHYR

Download         Length: 258 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9641.01 Da        Isoelectric Point: 5.1212

>AT267491 WP_214983341.1 NZ_CP115917:c2272532-2272284 [Tenacibaculum pacificus]
METVNYTDFRSNLKYWFDKVVNDVSDIIIKRKNGKDLVLISLDEYNSLKETTYLLTGKNRDILLNSIKELEQDKGVQKNL
IE

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References