Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2228287..2228504 Replicon chromosome
Accession NZ_CP115887
Organism Staphylococcus aureus strain C308

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag PCM89_RS11080 Protein ID WP_075583739.1
Coordinates 2228400..2228504 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2228287..2228342 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCM89_RS11055 2224409..2225074 - 666 WP_238612112.1 SDR family oxidoreductase -
PCM89_RS11060 2225226..2225546 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PCM89_RS11065 2225548..2226528 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
PCM89_RS11070 2226794..2227885 + 1092 WP_000495678.1 hypothetical protein -
- 2228287..2228342 + 56 - - Antitoxin
PCM89_RS11080 2228400..2228504 - 105 WP_075583739.1 hypothetical protein Toxin
PCM89_RS11085 2228602..2228763 - 162 Protein_2146 helix-turn-helix domain-containing protein -
PCM89_RS11090 2229181..2229339 + 159 WP_024928151.1 hypothetical protein -
PCM89_RS11095 2229999..2230856 - 858 WP_000370944.1 HAD family hydrolase -
PCM89_RS11100 2230924..2231706 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T267469 WP_075583739.1 NZ_CP115887:c2228504-2228400 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT267469 NZ_CP115887:2228287-2228342 [Staphylococcus aureus]
AAAAAGGGCAACACTCAGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References