Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF3/-
Location 1525656..1525955 Replicon chromosome
Accession NZ_CP115887
Organism Staphylococcus aureus strain C308

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag PCM89_RS07165 Protein ID WP_011447039.1
Coordinates 1525779..1525955 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1525656..1525711 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCM89_RS07135 1520890..1521105 - 216 WP_170267452.1 hypothetical protein -
PCM89_RS07140 1521284..1522294 - 1011 WP_000777019.1 restriction endonuclease subunit S -
PCM89_RS07145 1522281..1524185 - 1905 WP_001003363.1 N-6 DNA methylase -
PCM89_RS07150 1524546..1525301 - 756 WP_000861038.1 CHAP domain-containing protein -
PCM89_RS07155 1525313..1525567 - 255 WP_000611512.1 phage holin -
PCM89_RS07160 1525619..1525726 + 108 WP_001791821.1 hypothetical protein -
- 1525648..1525787 + 140 NuclAT_0 - -
- 1525648..1525787 + 140 NuclAT_0 - -
- 1525648..1525787 + 140 NuclAT_0 - -
- 1525648..1525787 + 140 NuclAT_0 - -
- 1525656..1525711 + 56 - - Antitoxin
PCM89_RS07165 1525779..1525955 - 177 WP_011447039.1 type I toxin-antitoxin system toxin PepG1 Toxin
PCM89_RS07170 1526108..1526407 - 300 WP_000466784.1 DUF2951 domain-containing protein -
PCM89_RS07175 1526453..1526617 - 165 WP_000916020.1 XkdX family protein -
PCM89_RS07180 1526610..1526999 - 390 WP_001166596.1 DUF2977 domain-containing protein -
PCM89_RS07185 1526999..1528465 - 1467 WP_000067127.1 BppU family phage baseplate upper protein -
PCM89_RS07190 1528465..1530375 - 1911 WP_000429558.1 minor structural protein -
PCM89_RS07195 1530391..1530681 - 291 WP_000179858.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1520890..1580451 59561


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T267459 WP_011447039.1 NZ_CP115887:c1525955-1525779 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 56 bp

>AT267459 NZ_CP115887:1525656-1525711 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References