Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2249988..2250205 Replicon chromosome
Accession NC_017351
Organism Staphylococcus aureus subsp. aureus 11819-97

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag MS7_RS11620 Protein ID WP_001802298.1
Coordinates 2250101..2250205 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2249988..2250043 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MS7_RS11600 2246125..2246790 - 666 WP_001024094.1 SDR family oxidoreductase -
MS7_RS11605 2246942..2247262 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
MS7_RS11610 2247264..2248244 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
MS7_RS11615 2248510..2249601 + 1092 WP_000495670.1 lytic regulatory protein -
- 2249988..2250043 + 56 - - Antitoxin
MS7_RS11620 2250101..2250205 - 105 WP_001802298.1 hypothetical protein Toxin
MS7_RS15205 2250885..2251043 + 159 WP_001792784.1 hypothetical protein -
MS7_RS11625 2251701..2252558 - 858 WP_000370929.1 Cof-type HAD-IIB family hydrolase -
MS7_RS11630 2252626..2253408 - 783 WP_000908179.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T26738 WP_001802298.1 NC_017351:c2250205-2250101 [Staphylococcus aureus subsp. aureus 11819-97]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T26738 NC_017351:c2250205-2250101 [Staphylococcus aureus subsp. aureus 11819-97]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT26738 NC_017351:2249988-2250043 [Staphylococcus aureus subsp. aureus 11819-97]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References