Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3658009..3658608 Replicon chromosome
Accession NZ_CP115713
Organism Rhodopseudomonas palustris strain k7

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OOZ54_RS17135 Protein ID WP_271100252.1
Coordinates 3658009..3658293 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OOZ54_RS17140 Protein ID WP_012496624.1
Coordinates 3658306..3658608 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOZ54_RS17110 (OOZ54_17110) 3653071..3653358 + 288 WP_271100248.1 hypothetical protein -
OOZ54_RS17115 (OOZ54_17115) 3653424..3654233 - 810 WP_271100249.1 DUF1295 domain-containing protein -
OOZ54_RS17120 (OOZ54_17120) 3654339..3654887 - 549 WP_271100250.1 hypothetical protein -
OOZ54_RS17125 (OOZ54_17125) 3654976..3656709 - 1734 WP_271100251.1 bifunctional protein-serine/threonine kinase/phosphatase -
OOZ54_RS17130 (OOZ54_17130) 3656777..3657616 - 840 WP_011158746.1 formate/nitrite transporter family protein -
OOZ54_RS17135 (OOZ54_17135) 3658009..3658293 + 285 WP_271100252.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OOZ54_RS17140 (OOZ54_17140) 3658306..3658608 + 303 WP_012496624.1 HigA family addiction module antitoxin Antitoxin
OOZ54_RS17145 (OOZ54_17145) 3658791..3659648 - 858 WP_271100253.1 SDR family oxidoreductase -
OOZ54_RS17150 (OOZ54_17150) 3659845..3661377 - 1533 WP_011158748.1 acyl-CoA carboxylase subunit beta -
OOZ54_RS17155 (OOZ54_17155) 3661657..3662073 + 417 WP_271100254.1 DUF4260 domain-containing protein -
OOZ54_RS17160 (OOZ54_17160) 3662075..3662350 - 276 WP_164604882.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-68)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10534.19 Da        Isoelectric Point: 10.6525

>T267339 WP_271100252.1 NZ_CP115713:3658009-3658293 [Rhodopseudomonas palustris]
MIQGFRGKFARAILHDRKAPKGLPADLLGTARRKLVQLNAAAALADLAIPPGNRLEALRGDLQGLHSIRINDQWRIVFRW
KDTGPEDVEIVDYH

Download         Length: 285 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11299.08 Da        Isoelectric Point: 8.9759

>AT267339 WP_012496624.1 NZ_CP115713:3658306-3658608 [Rhodopseudomonas palustris]
MTKKLPPVHPGEILREEFLLPMNLSPYAVAAACGVPRTRIERLARQETPVTADTALRLARYFGTTPNFWMNMQAQYDLEV
AEDNSADELRRIKPIKSKAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References