Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
Location | 4561906..4562606 | Replicon | chromosome |
Accession | NZ_CP115663 | ||
Organism | Pseudomonas putida strain PD584_L3 |
Toxin (Protein)
Gene name | mqsR | Uniprot ID | Q88F93 |
Locus tag | PED35_RS20770 | Protein ID | WP_010954960.1 |
Coordinates | 4562310..4562606 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | mqsA | Uniprot ID | I7AUJ7 |
Locus tag | PED35_RS20765 | Protein ID | WP_003254235.1 |
Coordinates | 4561906..4562307 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PED35_RS20745 (PED35_20745) | 4557040..4557861 | - | 822 | WP_010954957.1 | transporter substrate-binding domain-containing protein | - |
PED35_RS20750 (PED35_20750) | 4557937..4558866 | - | 930 | WP_010954958.1 | FAD-binding protein | - |
PED35_RS20755 (PED35_20755) | 4558867..4559616 | - | 750 | WP_003254232.1 | electron transfer flavoprotein subunit beta/FixA family protein | - |
PED35_RS20760 (PED35_20760) | 4560152..4561834 | + | 1683 | WP_010954959.1 | electron transfer flavoprotein-ubiquinone oxidoreductase | - |
PED35_RS20765 (PED35_20765) | 4561906..4562307 | - | 402 | WP_003254235.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
PED35_RS20770 (PED35_20770) | 4562310..4562606 | - | 297 | WP_010954960.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
PED35_RS20775 (PED35_20775) | 4562701..4564026 | - | 1326 | WP_010954961.1 | MFS transporter | - |
PED35_RS20780 (PED35_20780) | 4564099..4564578 | - | 480 | WP_010954962.1 | hypothetical protein | - |
PED35_RS20785 (PED35_20785) | 4564747..4565223 | - | 477 | WP_010954963.1 | sigma-70 family RNA polymerase sigma factor | - |
PED35_RS20790 (PED35_20790) | 4565436..4566614 | + | 1179 | WP_010954964.1 | efflux RND transporter periplasmic adaptor subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11133.22 Da Isoelectric Point: 10.2271
>T267233 WP_010954960.1 NZ_CP115663:c4562606-4562310 [Pseudomonas putida]
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL
Download Length: 297 bp
Antitoxin
Download Length: 134 a.a. Molecular weight: 14684.76 Da Isoelectric Point: 4.9531
>AT267233 WP_003254235.1 NZ_CP115663:c4562307-4561906 [Pseudomonas putida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA
Download Length: 402 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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