Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4561906..4562606 Replicon chromosome
Accession NZ_CP115663
Organism Pseudomonas putida strain PD584_L3

Toxin (Protein)


Gene name mqsR Uniprot ID Q88F93
Locus tag PED35_RS20770 Protein ID WP_010954960.1
Coordinates 4562310..4562606 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag PED35_RS20765 Protein ID WP_003254235.1
Coordinates 4561906..4562307 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PED35_RS20745 (PED35_20745) 4557040..4557861 - 822 WP_010954957.1 transporter substrate-binding domain-containing protein -
PED35_RS20750 (PED35_20750) 4557937..4558866 - 930 WP_010954958.1 FAD-binding protein -
PED35_RS20755 (PED35_20755) 4558867..4559616 - 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
PED35_RS20760 (PED35_20760) 4560152..4561834 + 1683 WP_010954959.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
PED35_RS20765 (PED35_20765) 4561906..4562307 - 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PED35_RS20770 (PED35_20770) 4562310..4562606 - 297 WP_010954960.1 type II toxin-antitoxin system MqsR family toxin Toxin
PED35_RS20775 (PED35_20775) 4562701..4564026 - 1326 WP_010954961.1 MFS transporter -
PED35_RS20780 (PED35_20780) 4564099..4564578 - 480 WP_010954962.1 hypothetical protein -
PED35_RS20785 (PED35_20785) 4564747..4565223 - 477 WP_010954963.1 sigma-70 family RNA polymerase sigma factor -
PED35_RS20790 (PED35_20790) 4565436..4566614 + 1179 WP_010954964.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11133.22 Da        Isoelectric Point: 10.2271

>T267233 WP_010954960.1 NZ_CP115663:c4562606-4562310 [Pseudomonas putida]
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT267233 WP_003254235.1 NZ_CP115663:c4562307-4561906 [Pseudomonas putida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q88F93

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References