Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2556416..2556600 Replicon chromosome
Accession NC_017347
Organism Staphylococcus aureus subsp. aureus T0131

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag SAT0131_RS13100 Protein ID WP_000482650.1
Coordinates 2556493..2556600 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2556416..2556476 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAT0131_RS13075 2551946..2552113 - 168 WP_001790576.1 hypothetical protein -
SAT0131_RS13085 2552344..2554077 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SAT0131_RS13090 2554102..2555865 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2556416..2556476 + 61 - - Antitoxin
SAT0131_RS13100 2556493..2556600 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
SAT0131_RS13105 2556734..2557120 - 387 WP_000779358.1 flippase GtxA -
SAT0131_RS13110 2557388..2558530 + 1143 WP_001176863.1 glycerate kinase -
SAT0131_RS13115 2558590..2559249 + 660 WP_000831298.1 membrane protein -
SAT0131_RS13120 2559431..2560642 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAT0131_RS13125 2560765..2561238 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T26714 WP_000482650.1 NC_017347:c2556600-2556493 [Staphylococcus aureus subsp. aureus T0131]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T26714 NC_017347:c2556600-2556493 [Staphylococcus aureus subsp. aureus T0131]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT26714 NC_017347:2556416-2556476 [Staphylococcus aureus subsp. aureus T0131]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References