Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2260802..2261019 Replicon chromosome
Accession NC_017347
Organism Staphylococcus aureus subsp. aureus T0131

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAT0131_RS11505 Protein ID WP_001802298.1
Coordinates 2260915..2261019 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2260802..2260857 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAT0131_RS11485 2256939..2257604 - 666 WP_001024094.1 SDR family oxidoreductase -
SAT0131_RS11490 2257756..2258076 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAT0131_RS11495 2258078..2259058 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SAT0131_RS11500 2259324..2260415 + 1092 WP_000495671.1 lytic regulatory protein -
- 2260802..2260857 + 56 - - Antitoxin
SAT0131_RS11505 2260915..2261019 - 105 WP_001802298.1 hypothetical protein Toxin
SAT0131_RS15815 2261180..2261663 - 484 Protein_2190 recombinase family protein -
SAT0131_RS11515 2261706..2262842 - 1137 WP_000115564.1 SAP domain-containing protein -
SAT0131_RS11520 2263131..2263223 + 93 WP_031872195.1 hypothetical protein -
SAT0131_RS11525 2263418..2264590 - 1173 WP_000195429.1 IS256-like element IS256 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2263418..2264590 1172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T26712 WP_001802298.1 NC_017347:c2261019-2260915 [Staphylococcus aureus subsp. aureus T0131]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T26712 NC_017347:c2261019-2260915 [Staphylococcus aureus subsp. aureus T0131]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT26712 NC_017347:2260802-2260857 [Staphylococcus aureus subsp. aureus T0131]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References