Detailed information of TA system TA026711

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2260756..2261019
• Replicon: chromosome
• Accession: NC_017347
• Organism: Staphylococcus aureus subsp. aureus T0131

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: SAT0131_RS11505
• Protein ID: WP_001802298.1
• Coordinates: 2260915..2261019 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	2260756..2260920 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAT0131_RS11485	2256939..2257604	-	666	WP_001024094.1	SDR family oxidoreductase	-
SAT0131_RS11490	2257756..2258076	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
SAT0131_RS11495	2258078..2259058	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
SAT0131_RS11500	2259324..2260415	+	1092	WP_000495671.1	lytic regulatory protein	-
-	2260756..2260920	+	165	-	-	Antitoxin
SAT0131_RS11505	2260915..2261019	-	105	WP_001802298.1	hypothetical protein	Toxin
SAT0131_RS15815	2261180..2261663	-	484	Protein_2190	recombinase family protein	-
SAT0131_RS11515	2261706..2262842	-	1137	WP_000115564.1	SAP domain-containing protein	-
SAT0131_RS11520	2263131..2263223	+	93	WP_031872195.1	hypothetical protein	-
SAT0131_RS11525	2263418..2264590	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2263418..2264590	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T26711 WP_001802298.1 NC_017347:c2261019-2260915 [Staphylococcus aureus subsp. aureus T0131]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T26711 NC_017347:c2261019-2260915 [Staphylococcus aureus subsp. aureus T0131]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 165 bp

>AT26711 NC_017347:2260756-2260920 [Staphylococcus aureus subsp. aureus T0131]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin