Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 11447..12147 Replicon chromosome
Accession NZ_CP115188
Organism Vibrio furnissii strain MT14

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag O8413_RS00045 Protein ID WP_237309414.1
Coordinates 11447..11857 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag O8413_RS00050 Protein ID WP_237309413.1
Coordinates 11854..12147 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O8413_RS00035 (O8413_00035) 7085..10123 + 3039 WP_237309417.1 site-specific integrase -
O8413_RS00040 (O8413_00040) 10144..11388 + 1245 WP_283512789.1 hypothetical protein -
O8413_RS00045 (O8413_00045) 11447..11857 - 411 WP_237309414.1 type II toxin-antitoxin system YafO family toxin Toxin
O8413_RS00050 (O8413_00050) 11854..12147 - 294 WP_237309413.1 hypothetical protein Antitoxin
O8413_RS00055 (O8413_00055) 12421..13020 - 600 WP_237309412.1 hypothetical protein -
O8413_RS00060 (O8413_00060) 13017..14180 - 1164 WP_237309411.1 DUF3596 domain-containing protein -
O8413_RS00065 (O8413_00065) 15120..16286 + 1167 WP_283512790.1 nucleotide sugar dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(33-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15820.00 Da        Isoelectric Point: 6.7631

>T267079 WP_237309414.1 NZ_CP115188:c11857-11447 [Vibrio furnissii]
VRTSLDIRVFKHKILIDALTESELHSLTKDFRCYKETGEKPDFFGRDEAYDHPNTLPILKSEEVKHIHLAANDAPFLSSI
QFYQTSDKHLVYCQGWNEPNCFLLIAILAPDAHEQARNRTIMHNLGLIAEKFRQHF

Download         Length: 411 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10617.01 Da        Isoelectric Point: 4.8303

>AT267079 WP_237309413.1 NZ_CP115188:c12147-11854 [Vibrio furnissii]
MKTSTIYAEKAVSSSEARKHFKDCLSGDPVVILSNNEPAGYMMSASFFEGLIKALEDKNAGSVSSFRPMSARLEVITHLN
AQALTELDEKTLGEFQE

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References