Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2414427..2414611 Replicon chromosome
Accession NC_017343
Organism Staphylococcus aureus subsp. aureus ECT-R 2

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag ECTR2_RS12190 Protein ID WP_000482652.1
Coordinates 2414504..2414611 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2414427..2414487 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECTR2_RS12165 2409882..2410049 - 168 Protein_2301 hypothetical protein -
ECTR2_RS12175 2410280..2412013 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
ECTR2_RS12180 2412038..2413801 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2414427..2414487 + 61 - - Antitoxin
ECTR2_RS12190 2414504..2414611 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
ECTR2_RS12195 2414745..2415131 - 387 WP_000779360.1 flippase GtxA -
ECTR2_RS12200 2415399..2416541 + 1143 WP_001176863.1 glycerate kinase -
ECTR2_RS12205 2416601..2417260 + 660 WP_000831298.1 membrane protein -
ECTR2_RS12210 2417442..2418653 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
ECTR2_RS12215 2418776..2419249 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T26694 WP_000482652.1 NC_017343:c2414611-2414504 [Staphylococcus aureus subsp. aureus ECT-R 2]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T26694 NC_017343:c2414611-2414504 [Staphylococcus aureus subsp. aureus ECT-R 2]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT26694 NC_017343:2414427-2414487 [Staphylococcus aureus subsp. aureus ECT-R 2]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References