Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
Location | 2388887..2389404 | Replicon | chromosome |
Accession | NC_017343 | ||
Organism | Staphylococcus aureus subsp. aureus ECT-R 2 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A3A3ATA4 |
Locus tag | ECTR2_RS12035 | Protein ID | WP_000113265.1 |
Coordinates | 2388887..2389153 (-) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | T1YB60 |
Locus tag | ECTR2_RS12040 | Protein ID | WP_000584499.1 |
Coordinates | 2389153..2389404 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECTR2_RS12010 | 2384315..2384851 | - | 537 | WP_000169317.1 | GNAT family N-acetyltransferase | - |
ECTR2_RS12015 | 2385085..2385909 | - | 825 | WP_000572038.1 | formate/nitrite transporter family protein | - |
ECTR2_RS12020 | 2386126..2386308 | - | 183 | WP_000230292.1 | hypothetical protein | - |
ECTR2_RS12025 | 2386392..2386859 | - | 468 | WP_000153347.1 | SRPBCC domain-containing protein | - |
ECTR2_RS12030 | 2387045..2388592 | - | 1548 | WP_000727772.1 | zinc ABC transporter substrate-binding lipoprotein AdcA | - |
ECTR2_RS14430 | 2388781..2388852 | - | 72 | Protein_2276 | hypothetical protein | - |
ECTR2_RS12035 | 2388887..2389153 | - | 267 | WP_000113265.1 | Txe/YoeB family addiction module toxin | Toxin |
ECTR2_RS12040 | 2389153..2389404 | - | 252 | WP_000584499.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
ECTR2_RS12045 | 2389569..2389670 | - | 102 | Protein_2279 | hypothetical protein | - |
ECTR2_RS12050 | 2389677..2390276 | - | 600 | WP_000162810.1 | DsbA family protein | - |
ECTR2_RS12055 | 2390295..2390657 | - | 363 | WP_000819843.1 | DUF4467 domain-containing protein | - |
ECTR2_RS12060 | 2390912..2392162 | + | 1251 | WP_001012225.1 | FemA/FemB family glycyltransferase FmhA | - |
ECTR2_RS12065 | 2392259..2392990 | - | 732 | WP_000615461.1 | amino acid ABC transporter ATP-binding protein | - |
ECTR2_RS12070 | 2392987..2393706 | - | 720 | WP_000479576.1 | amino acid ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10436.96 Da Isoelectric Point: 10.0573
>T26693 WP_000113265.1 NC_017343:c2389153-2388887 [Staphylococcus aureus subsp. aureus ECT-R 2]
MARLNITFSPQAFEDYKYFQQNNKKMVKKINELLKSIDRNGALEGIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIK
IASCKYHY
MARLNITFSPQAFEDYKYFQQNNKKMVKKINELLKSIDRNGALEGIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIK
IASCKYHY
Download Length: 267 bp
>T26693 NC_017343:c2389153-2388887 [Staphylococcus aureus subsp. aureus ECT-R 2]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACAATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACAATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9433.60 Da Isoelectric Point: 4.3407
>AT26693 WP_000584499.1 NC_017343:c2389404-2389153 [Staphylococcus aureus subsp. aureus ECT-R 2]
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKD
IDV
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKD
IDV
Download Length: 252 bp
>AT26693 NC_017343:c2389404-2389153 [Staphylococcus aureus subsp. aureus ECT-R 2]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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