Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2129322..2129538 Replicon chromosome
Accession NC_017343
Organism Staphylococcus aureus subsp. aureus ECT-R 2

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ECTR2_RS10680 Protein ID WP_001802298.1
Coordinates 2129434..2129538 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2129322..2129377 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECTR2_RS10660 2125528..2126193 - 666 WP_001024095.1 SDR family oxidoreductase -
ECTR2_RS10665 2126345..2126665 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ECTR2_RS10670 2126667..2127644 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
ECTR2_RS10675 2127910..2129001 + 1092 WP_000495669.1 hypothetical protein -
- 2129322..2129377 + 56 - - Antitoxin
ECTR2_RS10680 2129434..2129538 - 105 WP_001802298.1 hypothetical protein Toxin
ECTR2_RS14370 2130218..2130376 + 159 WP_001792784.1 hypothetical protein -
ECTR2_RS10685 2131034..2131891 - 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
ECTR2_RS10690 2131959..2132741 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T26691 WP_001802298.1 NC_017343:c2129538-2129434 [Staphylococcus aureus subsp. aureus ECT-R 2]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T26691 NC_017343:c2129538-2129434 [Staphylococcus aureus subsp. aureus ECT-R 2]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT26691 NC_017343:2129322-2129377 [Staphylococcus aureus subsp. aureus ECT-R 2]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References