Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 5135353..5135968 Replicon chromosome
Accession NZ_CP114886
Organism Endozoicomonas sp. GU-1 strain Ap1-3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag O2T12_RS21475 Protein ID WP_269675606.1
Coordinates 5135642..5135968 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag O2T12_RS21470 Protein ID WP_269675605.1
Coordinates 5135353..5135655 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2T12_RS21460 (O2T12_21460) 5130918..5133581 + 2664 WP_269675603.1 hypothetical protein -
O2T12_RS21465 (O2T12_21465) 5133995..5135284 + 1290 WP_269675604.1 outer membrane protein transport protein -
O2T12_RS21470 (O2T12_21470) 5135353..5135655 - 303 WP_269675605.1 NadS family protein Antitoxin
O2T12_RS21475 (O2T12_21475) 5135642..5135968 - 327 WP_269675606.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O2T12_RS21480 (O2T12_21480) 5136143..5136973 - 831 WP_269675964.1 amino acid ABC transporter ATP-binding protein -
O2T12_RS21485 (O2T12_21485) 5136996..5138086 - 1091 Protein_4193 amino acid ABC transporter permease -
O2T12_RS21490 (O2T12_21490) 5138098..5139214 - 1117 Protein_4194 amino acid ABC transporter permease -
O2T12_RS21495 (O2T12_21495) 5139440..5140465 - 1026 WP_269675608.1 amino acid ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(41-74)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12640.49 Da        Isoelectric Point: 8.8134

>T266885 WP_269675606.1 NZ_CP114886:c5135968-5135642 [Endozoicomonas sp. GU-1]
MEFVEASIFTKIITQLMSDDDYRAMQEAMIAQPDIGSVIRGTGGLRKFRWKLGDSGKRGGVRTIYYWQVHEETFYMLYAY
TKNRQKDLTSVEKKVLSELAREFCNERP

Download         Length: 327 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11527.29 Da        Isoelectric Point: 10.0938

>AT266885 WP_269675605.1 NZ_CP114886:c5135655-5135353 [Endozoicomonas sp. GU-1]
MSDHEFNFDELVESVREAIDINKGIKKPSRSFKYEEIDVFAIRKATHLSQEKFAALIGVSIKTVQSWEQKVRKPLGPARS
LLIMFRNNPDQAMALLHQSR

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References