Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1968500..1969091 Replicon chromosome
Accession NZ_CP114886
Organism Endozoicomonas sp. GU-1 strain Ap1-3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag O2T12_RS08530 Protein ID WP_269673417.1
Coordinates 1968780..1969091 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag O2T12_RS08525 Protein ID WP_101746508.1
Coordinates 1968500..1968787 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2T12_RS08500 (O2T12_08500) 1964207..1965046 - 840 WP_269673413.1 protein kinase -
O2T12_RS08505 (O2T12_08505) 1965215..1966513 + 1299 WP_269673414.1 FAD-binding oxidoreductase -
O2T12_RS08510 (O2T12_08510) 1966609..1967124 - 516 WP_269673415.1 hypothetical protein -
O2T12_RS08515 (O2T12_08515) 1967290..1967775 + 486 WP_269673416.1 hypothetical protein -
O2T12_RS08520 (O2T12_08520) 1967782..1968404 - 623 Protein_1667 DJ-1/PfpI family protein -
O2T12_RS08525 (O2T12_08525) 1968500..1968787 - 288 WP_101746508.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
O2T12_RS08530 (O2T12_08530) 1968780..1969091 - 312 WP_269673417.1 transcriptional regulator Toxin
O2T12_RS08535 (O2T12_08535) 1969197..1969538 - 342 WP_269673418.1 divalent-cation tolerance protein CutA -
O2T12_RS08540 (O2T12_08540) 1969636..1970694 - 1059 WP_269673419.1 methyltransferase domain-containing protein -
O2T12_RS08545 (O2T12_08545) 1970732..1971592 - 861 WP_269673420.1 MIP/aquaporin family protein -
O2T12_RS08550 (O2T12_08550) 1972558..1973937 + 1380 WP_269673421.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(29-95)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12034.82 Da        Isoelectric Point: 9.8865

>T266880 WP_269673417.1 NZ_CP114886:c1969091-1968780 [Endozoicomonas sp. GU-1]
MIFIETSRFTKLLSGYLSDDEYRVLQWHLQQKPDSGDLIRGSGGVRKIRWAPDGKGKSGSIRVIYYWKKSDFEIWMLTLY
RKSERESIPGHILKKVAEAINDE

Download         Length: 312 bp

>T266880 NZ_CP114886:c1969091-1968780 [Endozoicomonas sp. GU-1]
ATGATTTTCATAGAAACCAGCCGCTTTACCAAATTGCTATCCGGATATTTATCAGATGATGAATACCGGGTATTGCAGTG
GCACCTTCAACAGAAACCGGATTCTGGCGATCTTATCAGGGGTAGTGGGGGTGTCCGTAAAATACGATGGGCACCGGATG
GAAAGGGTAAAAGTGGTAGTATCCGGGTTATTTATTACTGGAAAAAGAGTGATTTTGAAATCTGGATGTTGACCTTATAT
CGCAAGTCGGAGCGTGAAAGTATTCCTGGTCATATCCTGAAAAAGGTAGCGGAGGCTATAAACGATGAATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10688.23 Da        Isoelectric Point: 9.9470

>AT266880 WP_101746508.1 NZ_CP114886:c1968787-1968500 [Endozoicomonas sp. GU-1]
MNERDIGQEILDGLNEIKAFKAGKGKLKTTVLSEPSPAKEIREKLQLSQSAFASFMGVSVRTIQDWEQGRRNPQGPAKAL
LRVVEQHPEVFENLR

Download         Length: 288 bp

>AT266880 NZ_CP114886:c1968787-1968500 [Endozoicomonas sp. GU-1]
ATGAATGAACGAGATATTGGTCAGGAAATCCTCGATGGCCTGAATGAGATCAAGGCATTTAAGGCGGGTAAGGGAAAGCT
GAAAACGACCGTCTTATCAGAGCCGTCACCTGCCAAAGAGATCAGGGAAAAGCTCCAGCTGTCCCAGTCGGCTTTTGCTT
CTTTTATGGGAGTCAGTGTTCGGACAATCCAGGACTGGGAGCAGGGACGGCGGAATCCTCAGGGGCCTGCAAAAGCTCTG
TTGCGAGTTGTCGAACAGCATCCTGAGGTTTTTGAGAATCTCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References