Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
Location | 2827337..2828567 | Replicon | chromosome |
Accession | NZ_CP114882 | ||
Organism | Flavobacterium lacustre strain IMCC36792 |
Toxin (Protein)
Gene name | HipT | Uniprot ID | - |
Locus tag | O6P34_RS12255 | Protein ID | WP_269684797.1 |
Coordinates | 2827337..2828260 (-) | Length | 308 a.a. |
Antitoxin (Protein)
Gene name | HipS | Uniprot ID | - |
Locus tag | O6P34_RS12260 | Protein ID | WP_269684798.1 |
Coordinates | 2828253..2828567 (-) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
O6P34_RS12245 | 2822451..2824442 | - | 1992 | WP_269684795.1 | hypothetical protein | - |
O6P34_RS12250 | 2824446..2827187 | - | 2742 | WP_269684796.1 | class I SAM-dependent DNA methyltransferase | - |
O6P34_RS12255 | 2827337..2828260 | - | 924 | WP_269684797.1 | HipA domain-containing protein | Toxin |
O6P34_RS12260 | 2828253..2828567 | - | 315 | WP_269684798.1 | HipA N-terminal domain-containing protein | Antitoxin |
O6P34_RS12265 | 2828570..2828779 | - | 210 | WP_269684799.1 | helix-turn-helix domain-containing protein | - |
O6P34_RS12270 | 2828955..2829716 | - | 762 | WP_269684800.1 | hypothetical protein | - |
O6P34_RS12275 | 2829716..2830372 | - | 657 | WP_269684801.1 | hypothetical protein | - |
O6P34_RS12280 | 2830379..2830783 | - | 405 | WP_269684802.1 | hypothetical protein | - |
O6P34_RS12285 | 2830836..2831123 | - | 288 | WP_269684803.1 | helix-turn-helix domain-containing protein | - |
O6P34_RS12290 | 2831334..2832437 | - | 1104 | WP_269684804.1 | hypothetical protein | - |
O6P34_RS12295 | 2832495..2833529 | - | 1035 | WP_269684805.1 | tyrosine-type recombinase/integrase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 35337.71 Da Isoelectric Point: 8.8601
>T266876 WP_269684797.1 NZ_CP114882:c2828260-2827337 [Flavobacterium lacustre]
MNRCPITYELCGTEKYSEKGLRMIAPKLTTLHDLPFTAAEQRQEAANRAKKLSIQGVQPKLSAVISVANQQFEIVDQFGN
YIIKPQSDIFPELPENEDVTMKMAKVYGLDVPLHGLVYSKDGSLSYFIKRFDRYSKGKKYATEDFAQLTESSRDTKYDYT
MEKLVKVIDEYCTFPAIEKADFFKRILFCFITGNEDMHLKNFSVITKAGKTTLTPVYDFLNSSISIKNPQEELALSLKGK
KSNFKSTELIDYYAKDRLGLNDKTVTTILYDMNKSLSKWTELVEVSFLSDSMKEKYLKVLDNRMKRF
MNRCPITYELCGTEKYSEKGLRMIAPKLTTLHDLPFTAAEQRQEAANRAKKLSIQGVQPKLSAVISVANQQFEIVDQFGN
YIIKPQSDIFPELPENEDVTMKMAKVYGLDVPLHGLVYSKDGSLSYFIKRFDRYSKGKKYATEDFAQLTESSRDTKYDYT
MEKLVKVIDEYCTFPAIEKADFFKRILFCFITGNEDMHLKNFSVITKAGKTTLTPVYDFLNSSISIKNPQEELALSLKGK
KSNFKSTELIDYYAKDRLGLNDKTVTTILYDMNKSLSKWTELVEVSFLSDSMKEKYLKVLDNRMKRF
Download Length: 924 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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