Detailed information of TA system TA026683

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1802744..1802924
• Replicon: chromosome
• Accession: NC_017343
• Organism: Staphylococcus aureus subsp. aureus ECT-R 2

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ECTR2_RS14835
• Protein ID: WP_001801861.1
• Coordinates: 1802744..1802839 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1802867..1802924 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ECTR2_RS08700	1797907..1798557	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
ECTR2_RS08705	1798638..1799633	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
ECTR2_RS08710	1799708..1800334	+	627	WP_000669024.1	hypothetical protein	-
ECTR2_RS08715	1800375..1800716	+	342	WP_000627540.1	DUF3969 family protein	-
ECTR2_RS08720	1800817..1801389	+	573	WP_000414216.1	hypothetical protein	-
ECTR2_RS14275	1801587..1802599	-	1013	Protein_1673	IS3 family transposase	-
ECTR2_RS14835	1802744..1802839	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1802867..1802924	-	58	-	-	Antitoxin
ECTR2_RS08740	1802962..1803063	+	102	WP_001792025.1	hypothetical protein	-
ECTR2_RS14695	1803041..1803202	-	162	Protein_1676	transposase	-
ECTR2_RS08745	1803193..1803687	-	495	Protein_1677	transposase	-
ECTR2_RS08750	1804139..1805368	-	1230	WP_000072627.1	restriction endonuclease subunit S	-
ECTR2_RS08755	1805361..1806917	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
ECTR2_RS08760	1807081..1807215	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1797149..1848280	51131

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T26683 WP_001801861.1 NC_017343:1802744-1802839 [Staphylococcus aureus subsp. aureus ECT-R 2]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T26683 NC_017343:1802744-1802839 [Staphylococcus aureus subsp. aureus ECT-R 2]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT26683 NC_017343:c1802924-1802867 [Staphylococcus aureus subsp. aureus ECT-R 2]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin