Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 5509257..5509848 Replicon chromosome
Accession NZ_CP114771
Organism Endozoicomonas sp. GU-1 strain Ap1-2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag O3276_RS23155 Protein ID WP_269673417.1
Coordinates 5509537..5509848 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag O3276_RS23150 Protein ID WP_101746508.1
Coordinates 5509257..5509544 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3276_RS23125 (O3276_23125) 5504964..5505803 - 840 WP_269673413.1 protein kinase -
O3276_RS23130 (O3276_23130) 5505972..5507270 + 1299 WP_269673414.1 FAD-binding oxidoreductase -
O3276_RS23135 (O3276_23135) 5507366..5507881 - 516 WP_269673415.1 hypothetical protein -
O3276_RS23140 (O3276_23140) 5508047..5508532 + 486 WP_269673416.1 hypothetical protein -
O3276_RS23145 (O3276_23145) 5508539..5509161 - 623 Protein_4518 DJ-1/PfpI family protein -
O3276_RS23150 (O3276_23150) 5509257..5509544 - 288 WP_101746508.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
O3276_RS23155 (O3276_23155) 5509537..5509848 - 312 WP_269673417.1 transcriptional regulator Toxin
O3276_RS23160 (O3276_23160) 5509954..5510295 - 342 WP_269673418.1 divalent-cation tolerance protein CutA -
O3276_RS23165 (O3276_23165) 5510393..5511451 - 1059 WP_269673419.1 methyltransferase domain-containing protein -
O3276_RS23170 (O3276_23170) 5511489..5512349 - 861 WP_269673420.1 MIP/aquaporin family protein -
O3276_RS23175 (O3276_23175) 5513315..5514694 + 1380 WP_269673421.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(29-95)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12034.82 Da        Isoelectric Point: 9.8865

>T266820 WP_269673417.1 NZ_CP114771:c5509848-5509537 [Endozoicomonas sp. GU-1]
MIFIETSRFTKLLSGYLSDDEYRVLQWHLQQKPDSGDLIRGSGGVRKIRWAPDGKGKSGSIRVIYYWKKSDFEIWMLTLY
RKSERESIPGHILKKVAEAINDE

Download         Length: 312 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10688.23 Da        Isoelectric Point: 9.9470

>AT266820 WP_101746508.1 NZ_CP114771:c5509544-5509257 [Endozoicomonas sp. GU-1]
MNERDIGQEILDGLNEIKAFKAGKGKLKTTVLSEPSPAKEIREKLQLSQSAFASFMGVSVRTIQDWEQGRRNPQGPAKAL
LRVVEQHPEVFENLR

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References