Detailed information of TA system TA266811

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/RelE-HTH
• Location: 2583812..2584427
• Replicon: chromosome
• Accession: NZ_CP114771
• Organism: Endozoicomonas sp. GU-1 strain Ap1-2

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: O3276_RS10660
• Protein ID: WP_269675606.1
• Coordinates: 2584101..2584427 (-)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: O3276_RS10655
• Protein ID: WP_269675605.1
• Coordinates: 2583812..2584114 (-)
• Length: 101 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (43-104)

Antitoxin

• Cro/C1-type helix-turn-helix domain (41-74)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12640.49 Da
• Isoelectric Point: 8.8134

>T266811 WP_269675606.1 NZ_CP114771:c2584427-2584101 [Endozoicomonas sp. GU-1]
MEFVEASIFTKIITQLMSDDDYRAMQEAMIAQPDIGSVIRGTGGLRKFRWKLGDSGKRGGVRTIYYWQVHEETFYMLYAY
TKNRQKDLTSVEKKVLSELAREFCNERP

Nucleotide

• Length: 327 bp

Antitoxin

Protein

• Length: 101 a.a.
• Molecular weight: 11527.29 Da
• Isoelectric Point: 10.0938

>AT266811 WP_269675605.1 NZ_CP114771:c2584114-2583812 [Endozoicomonas sp. GU-1]
MSDHEFNFDELVESVREAIDINKGIKKPSRSFKYEEIDVFAIRKATHLSQEKFAALIGVSIKTVQSWEQKVRKPLGPARS
LLIMFRNNPDQAMALLHQSR

Nucleotide

• Length: 303 bp