Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4776354..4776943 Replicon chromosome
Accession NZ_CP114600
Organism Xanthomonas oryzae pv. oryzae strain LA20

Toxin (Protein)


Gene name graT Uniprot ID G7TIR7
Locus tag O5966_RS22405 Protein ID WP_012443754.1
Coordinates 4776662..4776943 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag O5966_RS22400 Protein ID WP_011260746.1
Coordinates 4776354..4776644 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5966_RS22375 (O5966_22375) 4771552..4771878 - 327 WP_237384726.1 hypothetical protein -
O5966_RS22380 (O5966_22380) 4771947..4772981 - 1035 WP_011407587.1 IS630 family transposase -
O5966_RS22385 (O5966_22385) 4773249..4773581 + 333 WP_011260743.1 hypothetical protein -
O5966_RS22390 (O5966_22390) 4773741..4773928 + 188 Protein_4277 hypothetical protein -
O5966_RS22395 (O5966_22395) 4774031..4775425 - 1395 WP_075240796.1 type III secretion system effector XopQ -
O5966_RS22400 (O5966_22400) 4776354..4776644 - 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
O5966_RS22405 (O5966_22405) 4776662..4776943 - 282 WP_012443754.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O5966_RS22410 (O5966_22410) 4777038..4779296 - 2259 WP_075240794.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11066.83 Da        Isoelectric Point: 10.5318

>T266789 WP_012443754.1 NZ_CP114600:c4776943-4776662 [Xanthomonas oryzae pv. oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT266789 WP_011260746.1 NZ_CP114600:c4776644-4776354 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GFW5

Antitoxin

Source ID Structure

References