Detailed information of TA system TA026677

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2323689..2323886
• Replicon: chromosome
• Accession: NC_017342
• Organism: Staphylococcus aureus subsp. aureus TCH60

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: HMPREF0772_RS11690
• Protein ID: WP_000623369.1
• Coordinates: 2323779..2323886 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2323689..2323726 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HMPREF0772_RS11660	2318882..2319169	-	288	WP_000410718.1	hypothetical protein	-
HMPREF0772_RS14835	2319510..2319800	+	291	WP_001791476.1	hypothetical protein	-
HMPREF0772_RS11670	2319888..2320529	-	642	WP_000571183.1	ABC transporter ATP-binding protein	-
HMPREF0772_RS11675	2320526..2320846	-	321	WP_000873929.1	YxeA family protein	-
HMPREF0772_RS11680	2320849..2322813	-	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
HMPREF0772_RS14840	2322857..2323129	-	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
HMPREF0772_RS11685	2323139..2323240	-	102	WP_001790623.1	hypothetical protein	-
-	2323689..2323726	+	38	-	-	Antitoxin
HMPREF0772_RS11690	2323779..2323886	-	108	WP_000623369.1	putative holin-like toxin	Toxin
HMPREF0772_RS11695	2324157..2324759	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
HMPREF0772_RS11700	2324774..2324950	-	177	WP_000214898.1	YkvS family protein	-
HMPREF0772_RS11705	2325149..2326135	+	987	WP_000668820.1	lipoate--protein ligase	-
HMPREF0772_RS11710	2326216..2326434	-	219	WP_000876825.1	IDEAL domain-containing protein	-
HMPREF0772_RS11715	2326644..2327213	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T26677 WP_000623369.1 NC_017342:c2323886-2323779 [Staphylococcus aureus subsp. aureus TCH60]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T26677 NC_017342:c2323886-2323779 [Staphylococcus aureus subsp. aureus TCH60]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 38 bp

>AT26677 NC_017342:2323689-2323726 [Staphylococcus aureus subsp. aureus TCH60]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin